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NCT03723642: OSAE
Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence
NA trial testing Initial serum malondialdehyde level in Appendicitis Acute in 40 participants. Status unknown.
1 October 2020
Quick facts
| Lead sponsor | Medical University of Graz |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 40 |
| Start date | 2 October 2019 |
| Primary completion | 1 October 2020 |
| Estimated completion | 1 December 2020 |
| Sites | 1 location across Austria |
Drugs / interventions tested
- Initial serum malondialdehyde level
- Final serum malondialdehyde level
- Initial differential white blood cell count
- Final differential white blood cell count
- Initial c-reactive protein serum level
- Final c-reactive protein serum level
- Initial VOC
- VOC 5min
- VOC 15min
- VOC 30min
- VOC 45min
- Final VOC
Conditions studied
- Appendicitis Acute — all drugs for Appendicitis Acute →
Sponsor
Medical University of Graz
Who can join
Adults 6 to 18, any sex, with Appendicitis Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In the planned prospective randomized study, oxidative stress will be investigated by analyzing volatile organic compounds in the exhaled air in children. Children who have undergone open versus laparoscopic surgery for appendicitis will be compared. A better understanding of the effects of the surgical technique could be a prerequisite for an optimized surgical setting. It could also lead to recommendations for pre- or perioperatively antioxidative agents.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03723642
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Appendicitis Acute
Currently open trials in the same condition.
- NCT07521969 — Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial. · NA · recruiting
- NCT06815822 — Prevention of Postoperative Hernias in Emergency Surgery · recruiting
- NCT06948071 — Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis · NA · recruiting
- NCT06762275 — The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care · NA · recruiting
- NCT06395636 — Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients · NA · recruiting
Other Medical University of Graz trials
Trials by the same sponsor.
- NCT07498244 — Collagen Fingerprinting for Stratification of Pulmonary Hypertension (PH) Patients · recruiting
- NCT07492823 — Clinical Applicability of Liquid Biopsy in Chondrosarcoma · not yet recruiting
- NCT07297615 — 3D Liver Volumetry · NA · not yet recruiting
- NCT07588282 — The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intention · NA · recruiting
- NCT07376096 — Liquid Biopsy in Germ Cell Tumors · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03723642 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of Graz
- Last refreshed: 15 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03723642.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing