NCT03723031 is a Phase 2 clinical trial of Misoprostol in Hemorrhage, Postpartum, sponsored by Cairo University.

Who is sponsoring NCT03723031?

NCT03723031 is sponsored by Cairo University.

What drugs are being tested in NCT03723031?

Interventions in NCT03723031: Misoprostol.

What condition does NCT03723031 study?

NCT03723031 studies Hemorrhage, Postpartum.

Is NCT03723031 still recruiting?

NCT03723031 is currently status unknown. Last updated 18 March 2020.

Last reviewed 2020-03-18 · How we verify

NCT03723031

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intrauterine Misoprostol Versus Rectal Misoprostol in Reducing Blood Loss During Cesarean Section

Status unknown Phase 2 Last updated 18 March 2020

What this trial tests

Phase 2 trial testing Misoprostol in Hemorrhage, Postpartum in 98 participants. Status unknown.

Timeline

15 November 2018

Primary endpoint
15 April 2020

15 May 2020

Quick facts

Lead sponsor	Cairo University
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	98
Start date	15 November 2018
Primary completion	15 April 2020
Estimated completion	15 May 2020
Sites	1 location across Egypt

Drugs / interventions tested

Misoprostol (Misoprostol) — full drug profile →

Conditions studied

Hemorrhage, Postpartum — all drugs for Hemorrhage, Postpartum →

Sponsor

Cairo University

Who can join

Adults 20 to 40, female only, with Hemorrhage, Postpartum. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

98 pregnant women attending for CS will be randomized into 2 groups. Rectal misopristol group who will receive 400 microgram misoprostol rectally preoperatively with urinary catheter insertion and intrauterine misopristol group will receive 400 microgram misoprostol intrauterine (200 microgram at each cornu) intraoperatively following the delivery of the placenta. The estimated blood loss for each patient will be measured and data of both groups will be compared.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A comparative study between preoperative rectal misoprostol and intraoperative intrauterine administration in the reduction of blood loss during and after cesarean delivery: A randomized controlled trial.
El-Sherbini MM, Maged AM, Helal OM, Awad MO, et al · · 2021 · cited 5× · PMID 33064852 · DOI 10.1002/ijgo.13426

Verify or expand the search:

Other trials of Misoprostol

Trials testing the same drug.

NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting

Other recruiting trials for Hemorrhage, Postpartum

Currently open trials in the same condition.

NCT06452355 — Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage · NA · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03723031 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 18 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03723031.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing