NCT03722134

Mechanochemical Ablation vs Thermal Ablation

Completed NA Last updated 10 February 2021

What this trial tests

NA trial testing MOCA in Varicose Veins of Lower Limb in 132 participants. Completed in 31 December 2020.

Timeline

31 January 2014

Primary endpoint
31 December 2020

31 December 2020

Quick facts

Lead sponsor	Helsinki University Central Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	132
Start date	31 January 2014
Primary completion	31 December 2020
Estimated completion	31 December 2020

Drugs / interventions tested

• MOCA
• EVLA
• RFA

Conditions studied

• Varicose Veins of Lower Limb — all drugs for Varicose Veins of Lower Limb →

Sponsor

Helsinki University Central Hospital

Who can join

Adults 20 to 75, any sex, with Varicose Veins of Lower Limb. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with GSV reflux were randomized to undergo either MOCA or thermal ablation with laser or radiofrequency. The main outcome measure was the occlusion rate of the GSV at one year.Patients with GSV reflux were randomized to undergo either MOCA or thermal ablation with laser or radiofrequency. The main outcome measure was the occlusion rate of the GSV at one and three years.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Randomized clinical trial of mechanochemical and endovenous thermal ablation of great saphenous varicose veins.
   Vähäaho S, Mahmoud O, Halmesmäki K, Albäck A, et al · · 2019 · cited 27× · PMID 30908611 · DOI 10.1002/bjs.11158