NCT03720223 is a Phase 3 clinical trial of Liposomal Bupivacaine in Urethral Stricture, sponsored by Urology of Virginia.

Who is sponsoring NCT03720223?

NCT03720223 is sponsored by Urology of Virginia.

What drugs are being tested in NCT03720223?

Interventions in NCT03720223: Liposomal Bupivacaine.

What condition does NCT03720223 study?

NCT03720223 studies Urethral Stricture.

Is NCT03720223 still recruiting?

NCT03720223 is currently completed. Last updated 1 October 2021.

Last reviewed 2021-10-01 · How we verify

NCT03720223

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Liposomal Bupivacaine To Control Post-Operative Pain Following BMG

Completed Phase 3 Last updated 1 October 2021

What this trial tests

Phase 3 trial testing Liposomal Bupivacaine in Urethral Stricture in 50 participants. Completed in 31 October 2017.

Timeline

20 January 2015

Primary endpoint
31 October 2017

31 October 2017

Quick facts

Lead sponsor	Urology of Virginia
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	50
Start date	20 January 2015
Primary completion	31 October 2017
Estimated completion	31 October 2017
Sites	1 location across United States

Drugs / interventions tested

Liposomal Bupivacaine — full drug profile →

Conditions studied

Urethral Stricture — all drugs for Urethral Stricture →

Sponsor

Urology of Virginia — full company profile →

Who can join

18 and older, male only, with Urethral Stricture. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a single blinded-randomized controlled trial that recruit male patients for substitution urethroplasty using buccal mucosal graft. The study investigators aim to assess the efficacy and safety of liposomal bupivacaine injection to the buccal graft harvest site on post-operative main score, morphine equivalence requirement and oral morbidities.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Liposomal Bupivacaine Local Infiltration for Buccal Mucosal Graft Harvest Site Pain Control: A Single-blinded Randomized Controlled Trial.
Chua ME, Zuckerman JM, Strehlow R, Virasoro R, et al · · 2020 · cited 5× · PMID 32692990 · DOI 10.1016/j.urology.2020.06.067
Abstracts from the 39th Congress of the Société Internationale d'Urologie, Athens, Greece, October 17-20, 2019.
· 2019 · PMID 31620861 · DOI 10.1007/s00345-019-02955-9

Verify or expand the search:

Other trials of Liposomal Bupivacaine

Trials testing the same drug.

NCT06284434 — Liposomal Bupivacaine Use in Alveolar Bone Graft Patients · Phase 3 · recruiting
NCT05891613 — A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction · Phase 4 · completed
NCT06411795 — Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatodu · Phase 2 · recruiting
NCT05177991 — Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs · EARLY_PHASE1 · active not recruiting
NCT05044468 — EXPAREL or Lidocane as Local Anesthetic in Patients Undergoing Pleuroscopy With Pleural Biopsy and Indwelling Pleural Ca · Phase 2 · active not recruiting

Other recruiting trials for Urethral Stricture

Currently open trials in the same condition.

NCT07403786 — Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction · recruiting
NCT07074717 — Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture · NA · recruiting
NCT06362083 — Urethral Stricture Database · recruiting
NCT05383274 — Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters · Phase 4 · recruiting
NCT04965025 — Multi-stage Urethroplasty with Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03720223 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Urology of Virginia
Last refreshed: 1 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03720223.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing