NCT03718988 (SWAP-MEAT) is a NA clinical trial of Meat products in Microbiome, sponsored by Stanford University.

Who is sponsoring NCT03718988?

NCT03718988 is sponsored by Stanford University.

What drugs are being tested in NCT03718988?

Interventions in NCT03718988: Meat products, Plant Alternative products.

What condition does NCT03718988 study?

NCT03718988 studies Microbiome, Immune Function, Cardiovascular Diseases.

Is NCT03718988 still recruiting?

NCT03718988 is currently completed. Last updated 21 February 2023.

Last reviewed 2023-02-21 · How we verify

NCT03718988: SWAP-MEAT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial

Completed NA Last updated 21 February 2023

What this trial tests

NA trial testing Meat products in Microbiome in 38 participants. Completed in 5 December 2019.

Timeline

17 January 2019

Primary endpoint
5 December 2019

5 December 2019

Quick facts

Lead sponsor	Stanford University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	prevention
Enrollment	38
Start date	17 January 2019
Primary completion	5 December 2019
Estimated completion	5 December 2019
Sites	1 location across United States

Drugs / interventions tested

Meat products
Plant Alternative products

Conditions studied

Microbiome — all drugs for Microbiome →
Immune Function — all drugs for Immune Function →
Cardiovascular Diseases — all drugs for Cardiovascular Diseases →

Sponsor

Stanford University

Who can join

18 and older, any sex, with Microbiome or Immune Function. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to investigate the impact of replacing meat consumption with plant-based meat alternative consumption on cardiovascular health, the gut microbiome, and metabolic status.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

A randomized crossover trial on the effect of plant-based compared with animal-based meat on trimethylamine-N-oxide and cardiovascular disease risk factors in generally healthy adults: Study With Appetizing Plantfood-Meat Eating Alternative Trial (SWAP-MEAT).
Crimarco A, Springfield S, Petlura C, Streaty T, et al · · 2020 · cited 176× · PMID 32780794 · DOI 10.1093/ajcn/nqaa203
Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis.
Jiang Z, Zhao M, Voilquin L, Jung Y, et al · · 2021 · cited 93× · PMID 34348115 · DOI 10.1016/j.cmet.2021.07.010
The path toward using microbial metabolites as therapies.
Descamps HC, Herrmann B, Wiredu D, Thaiss CA. · · 2019 · cited 77× · PMID 31201140 · DOI 10.1016/j.ebiom.2019.05.063
Urinary Response to Consuming Plant-Based Meat Alternatives in Persons with Normal Kidney Function: The SWAP-MEAT Pilot Trial.
Ward CP, Landry MJ, Cunanan KM, Raphael KL, et al · · 2024 · cited 5× · PMID 39514692 · DOI 10.2215/cjn.0000000000000532

Verify or expand the search:

Other recruiting trials for Microbiome

Currently open trials in the same condition.

NCT07501455 — Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolera · NA · recruiting
NCT07439718 — The Effects of an Oral Nutritional Intervention on the Small Intestine Microbiome · NA · recruiting
NCT07209007 — Dynamics of Dysbiosis in the Skin and Gut Microbiome of Burn Patients · recruiting
NCT06778083 — STI Prophylaxis and Emergence of Antimicrobial Resistance · recruiting
NCT06606119 — The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma · recruiting

Other Stanford University trials

Trials by the same sponsor.

NCT05945147 — Ketamine and Midazolam Infusions for CRPS: Feasibility Study · Phase 2 · withdrawn
NCT04225949 — Patients Understanding of PROM Graphs · NA · withdrawn
NCT06273098 — School-Based Bladder Health Intervention · NA · withdrawn
NCT04652635 — Management of Nailbed Injuries · NA · withdrawn
NCT05443503 — Stanford Spine Keeper - Managing Your Low Back Pain · NA · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03718988 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Stanford University
Last refreshed: 21 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03718988.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing