Last reviewed · How we verify
NCT03717545
Second Transplantation for Graft Failure
NA trial testing second allogeneic stem cell transplantation in Graft Failure in 12 participants. Status unknown.
31 December 2020
Quick facts
| Lead sponsor | Peking University People's Hospital |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 12 |
| Start date | 1 March 2018 |
| Primary completion | 31 December 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across China |
Drugs / interventions tested
- second allogeneic stem cell transplantation
Conditions studied
- Graft Failure — all drugs for Graft Failure →
- Stem Cell Transplant Complications — all drugs for Stem Cell Transplant Complications →
Sponsor
Peking University People's Hospital
Who can join
Eligibility, any sex, with Graft Failure or Stem Cell Transplant Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Graft failure is a lethal complication after allogeneic stem cell transplantation, which often need a salvage transplantation. However, the current outcome of second transplantation for graft failure is far from satisfactory. We performed a prospective single-arm study to investigate the safety and efficacy of a novel regimen.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Graft Failure in Patients With Hematological Malignancies: A Successful Salvage With a Second Transplantation From a Different Haploidentical Donor.
Sun YQ, Wang Y, Wang FR, Yan CH, et al · · 2021 · cited 17× · PMID 34150785 · DOI 10.3389/fmed.2021.604085 -
Advances in second hematopoietic stem cell transplantation.
Yan S, Zhu X, Xiao Y. · · 2024 · cited 1× · PMID 39044835 · DOI 10.3389/fimmu.2024.1428101
Verify or expand the search:
- PubMed search for NCT03717545
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of second allogeneic stem cell transplantation
Trials testing the same drug.
- NCT06512545 — Modified Second Haplo-transplantation for Graft Failure · NA · recruiting
Other recruiting trials for Graft Failure
Currently open trials in the same condition.
- NCT06800430 — Graft Failure and Consequences of Coronary Artery Bypass Graft Surgery · recruiting
- NCT06872333 — Allo HSCT for High Risk Hemoglobinopathies · Phase 2 · recruiting
- NCT06512545 — Modified Second Haplo-transplantation for Graft Failure · NA · recruiting
- NCT06676696 — Study to Compare the Outcome of Receiving Continued Immunosuppression Versus Stopping Immunosuppression at 6 Months to S · Phase 4 · recruiting
- NCT06179329 — One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG · NA · recruiting
Other Peking University People's Hospital trials
Trials by the same sponsor.
- NCT07535645 — Baricitinib for Post-HSCT Persistent Thrombocytopenia · Phase 1, PHASE2 · not yet recruiting
- NCT07516002 — Immunoglobulin Efficacy and Immune Profiling in Antibody Immunodeficiency · not yet recruiting
- NCT07294339 — A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positiv · NA · not yet recruiting
- NCT07500441 — Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML · recruiting
- NCT07487883 — Cadherin 3(CDH3)-Targeted PET in Lung Malignant Tumors · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03717545 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking University People's Hospital
- Last refreshed: 24 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03717545.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing