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NCT03716557
A High Frequency Spinal Cord Stimulation PET-CT Scan Study
NA trial testing Spinal Cord Stimulation 4000Hz in Neuropathic Pain in 22 participants. Completed in 31 January 2020.
31 January 2020
Quick facts
| Lead sponsor | Barts & The London NHS Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 9 February 2018 |
| Primary completion | 31 January 2020 |
| Estimated completion | 31 January 2020 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Spinal Cord Stimulation 4000Hz
- Spinal Cord Stimulation 10000Hz
- Spinal Cord Stimulation 40Hz
Conditions studied
- Neuropathic Pain — all drugs for Neuropathic Pain →
Sponsor
Barts & The London NHS Trust — full company profile →
Who can join
Adults 18 to 75, any sex, with Neuropathic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the clinical response to Spinal Cord Stimulation frequency parameters: 40Hz, 4000Hz and 10000Hz and explore the brain imaging changes using PET-CT scans. The response to these stimulator settings on health related quality of life will also be measured using validated questionnaires.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Dynamic Brain Imaging Response to Spinal Cord Stimulation Differential Frequencies DiFY SCS-PET Clinical Trial.
Poply K, Haroon A, Ganeshan B, Nikolic S, et al · · 2023 · cited 3× · PMID 36151010 · DOI 10.1016/j.neurom.2022.07.012
Verify or expand the search:
- PubMed search for NCT03716557
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Barts & The London NHS Trust trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03716557 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Barts & The London NHS Trust
- Last refreshed: 9 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03716557.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing