NCT03714841

C-reactive Protein Information and Blood Cultures for Emergency Department Patients With Sepsis

Status unknown NA Last updated 20 November 2020

What this trial tests

NA trial testing CRP in Sepsis in 208 participants. Status unknown.

Timeline

21 January 2017

Primary endpoint
15 September 2020

15 May 2021

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	208
Start date	21 January 2017
Primary completion	15 September 2020
Estimated completion	15 May 2021
Sites	2 locations across Canada

Drugs / interventions tested

• CRP

Conditions studied

• Sepsis — all drugs for Sepsis →
• Infection — all drugs for Infection →
• Bacteremia — all drugs for Bacteremia →

Sponsor

University of British Columbia

Who can join

19 and older, any sex, with Sepsis or Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with sepsis (2 or more systemic inflammatory response syndrome criteria and suspected infection) assessed in the emergency department have blood cultures obtained to identify potential blood stream infections (BSI). Blood cultures are expensive, sometimes inaccurate, and only positive about 10% of the time in the emergency department.

This study evaluates the effect of physician knowledge of C-reactive protein (CRP) levels on ordering rates of blood cultures in emergency department patients with sepsis. All patients with sepsis will have CRP levels measured using a point-of-care device, prior to blood tests being ordered. Half of participants will have their CRP level available to the emergency physician and half will not. Blood culture ordering rate and safety outcomes will be compared between these two groups.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.