Who is sponsoring NCT03713268?

NCT03713268 is sponsored by Duke University.

What drugs are being tested in NCT03713268?

Interventions in NCT03713268: Microscope integrated optical coherence tomography.

What condition does NCT03713268 study?

NCT03713268 studies Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment, Retinal Disease, Preretinal Fibrosis, Cataract, Ocular Tumor, Strabismus, Healthy.

Is NCT03713268 still recruiting?

NCT03713268 is currently recruiting now. Last updated 6 October 2025.

Last reviewed 2025-10-06 · How we verify

NCT03713268: MIOCT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intraoperative OCT Guidance of Intraocular Surgery II

Recruiting now Last updated 6 October 2025

What this trial tests

trial testing Microscope integrated optical coherence tomography in Macular Holes in 262 participants. Currently enrolling.

Timeline

30 September 2018

Primary endpoint
31 December 2026

31 May 2027

Quick facts

Lead sponsor	Duke University
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	262
Start date	30 September 2018
Primary completion	31 December 2026
Estimated completion	31 May 2027
Sites	1 location across United States

Drugs / interventions tested

Microscope integrated optical coherence tomography

Conditions studied

Macular Holes — all drugs for Macular Holes →
Epiretinal Membrane — all drugs for Epiretinal Membrane →
Diabetic Retinopathy — all drugs for Diabetic Retinopathy →
Retinal Detachment — all drugs for Retinal Detachment →

Sponsor

Duke University

Who can join

4 Weeks and older, any sex, with Macular Holes or Epiretinal Membrane. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical visualization.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Quantitative measurements of intraocular structures and microinjection bleb volumes using intraoperative optical coherence tomography.
Li JD, Raynor W, Dhalla AH, Viehland C, et al · · 2023 · cited 11× · PMID 36698674 · DOI 10.1364/boe.483278
Visualization of surgical maneuvers using intraoperative real-time volumetric optical coherence tomography.
Li JD, Viehland C, Dhalla AH, Trout R, et al · · 2023 · cited 9× · PMID 37497507 · DOI 10.1364/boe.488967

Verify or expand the search:

Other recruiting trials for Macular Holes

Currently open trials in the same condition.

NCT06211907 — Small Macular Holes Treated With Air · NA · recruiting
NCT06000111 — Duration of Face Down Positioning for Full-Thickness Macular Hole Repair · NA · recruiting
NCT04904679 — The Use of Amniotic Membrane or Internal Limiting Membrane for Large or Refractory Macular Holes: A Prospective Study · NA · active not recruiting

Other Duke University trials

Trials by the same sponsor.

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NCT07519317 — Dosing and Deployment Trial: A Home-based Optokinetic Treatment · NA · not yet recruiting
NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07216963 — The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · NA · not yet recruiting
NCT07459218 — IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03713268 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 6 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03713268.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing