NCT03713216 is a Phase 4 clinical trial of Naldebain in Pain, Postoperative, sponsored by Cathay General Hospital.

Who is sponsoring NCT03713216?

NCT03713216 is sponsored by Cathay General Hospital.

What drugs are being tested in NCT03713216?

Interventions in NCT03713216: Naldebain, Morphine.

What condition does NCT03713216 study?

NCT03713216 studies Pain, Postoperative.

Is NCT03713216 still recruiting?

NCT03713216 is currently completed. Last updated 16 July 2020.

Last reviewed 2020-07-16 · How we verify

NCT03713216

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic Cholecystectomy

Completed Phase 4 Last updated 16 July 2020

What this trial tests

Phase 4 trial testing Naldebain in Pain, Postoperative in 44 participants. Completed in 1 January 2020.

Timeline

1 July 2018

Primary endpoint
1 October 2019

1 January 2020

Quick facts

Lead sponsor	Cathay General Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	44
Start date	1 July 2018
Primary completion	1 October 2019
Estimated completion	1 January 2020
Sites	1 location across Taiwan

Drugs / interventions tested

Naldebain — full drug profile →
Morphine

Conditions studied

Pain, Postoperative — all drugs for Pain, Postoperative →

Sponsor

Cathay General Hospital

Who can join

20 and older, any sex, with Pain, Postoperative. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To determine the effect and safety of NALDEBAIN versus Morphine as needed in patients after laparoscopic cholecystectomy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Preoperative Administration of Extended-Release Dinalbuphine Sebacate Compares with Morphine for Post-Laparoscopic Cholecystectomy Pain Management: A Randomized Study.
Lee SO, Huang LP, Wong CS. · · 2020 · cited 16× · PMID 32982387 · DOI 10.2147/jpr.s263315

Verify or expand the search:

Other trials of Naldebain

Trials testing the same drug.

NCT05842733 — A Novel, Potent and Non-addictive Analgesic of Combinations for Knee Replacement Moderate to Severe Pain Management · Phase 2 · unknown
NCT03854851 — NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis · Phase 4 · unknown

Other recruiting trials for Pain, Postoperative

Currently open trials in the same condition.

NCT07512141 — Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy · NA · recruiting
NCT07354581 — Erector Spinae Plane Block vs Quadro-Iliac Plane Block After Lumbar Instrumentation Surgery · NA · recruiting
NCT07239817 — PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach · NA · recruiting
NCT06740214 — Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty · Phase 3 · recruiting
NCT07057557 — Aloe Vera vs Paraffin Tulle Dressings for Pain Management in Split Thickness Skin Graft Donor Sites · NA · recruiting

Other Cathay General Hospital trials

Trials by the same sponsor.

NCT05338463 — Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients · Phase 4 · completed
NCT05540236 — Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic · NA · completed
NCT05241782 — The Effect of Auricular Acupressure on the Improvement of Anxiousness, Depression and Heart Rate Variability in Stroke P · NA · unknown
NCT05374629 — Study on the Effect of Smoking Cessation in COPD Patients After Shared Decision Making Intervention · NA · completed
NCT04535765 — Effect of Early Warm Water Sitz Bath on Urinary Retention After Hemorrhoidectomy · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03713216 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cathay General Hospital
Last refreshed: 16 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03713216.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing