NCT03712579 is a NA clinical trial of SFA-Rich Meal in Inflammation, sponsored by Loughborough University.

Who is sponsoring NCT03712579?

NCT03712579 is sponsored by Loughborough University.

What drugs are being tested in NCT03712579?

Interventions in NCT03712579: SFA-Rich Meal, MUFA-Rich Meal.

What condition does NCT03712579 study?

NCT03712579 studies Inflammation, Obesity, Inflammatory Response, Cardiovascular Diseases, Overweight.

Is NCT03712579 still recruiting?

NCT03712579 is currently completed. Last updated 17 May 2022.

Last reviewed 2022-05-17 · How we verify

NCT03712579

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of High-fat Meals Varying in Fatty Acid Composition on Adipose and Systemic Metabolic-inflammatory Responses

Completed NA Last updated 17 May 2022

What this trial tests

NA trial testing SFA-Rich Meal in Inflammation in 8 participants. Completed in 15 October 2020.

Timeline

21 January 2019

Primary endpoint
15 October 2020

15 October 2020

Quick facts

Lead sponsor	Loughborough University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	8
Start date	21 January 2019
Primary completion	15 October 2020
Estimated completion	15 October 2020
Sites	1 location across United Kingdom

Drugs / interventions tested

SFA-Rich Meal
MUFA-Rich Meal

Conditions studied

Inflammation — all drugs for Inflammation →
Obesity — all drugs for Obesity →
Inflammatory Response — all drugs for Inflammatory Response →
Cardiovascular Diseases — all drugs for Cardiovascular Diseases →

Sponsor

Loughborough University

Who can join

Adults 18 to 50, any sex, with Inflammation or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiometabolic disorders are a leading cause of death worldwide. Replacing saturated fatty acids (SFA) with unsaturated fatty acids is recommended as a way of lowering cardiometabolic disease risk. Consuming a diet rich in SFA may lead to a greater metabolic-inflammatory response in white adipose tissue during the fasting state, when compared to eating a diet rich in monounsaturated fatty acids (MUFA). Since individuals spend most of the day in the fed (or postprandial) state, it is important to see how different types of dietary fatty acids affect postprandial white adipose tissue and systemic metabolic-inflammatory responses. This study will investigate the effect of a SFA-rich meal on markers of white adipose tissue and systemic metabolic-inflammation, compared to a MUFA-rich meal in overweight adults. In a randomised, single blind controlled, cross-over manner participants will consume either a SFA- or MUFA-rich meal and sequential blood and white adipose tissue samples will be collected before and until 6 hours postprandially.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other Loughborough University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03712579 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Loughborough University
Last refreshed: 17 May 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03712579.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing