Who is sponsoring NCT03712007?

NCT03712007 is sponsored by University of Sao Paulo.

What drugs are being tested in NCT03712007?

Interventions in NCT03712007: MAMP therapy with MARPE expander, MAMP therapy with Hyrax expander.

What condition does NCT03712007 study?

NCT03712007 studies Malocclusion, Angle Class III, Crossbite (Anterior) (Posterior).

Is NCT03712007 still recruiting?

NCT03712007 is currently completed. Last updated 12 May 2021.

Last reviewed 2021-05-12 · How we verify

NCT03712007

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Two Miniscrew Anchored Maxillary Protraction Protocols

Completed NA Last updated 12 May 2021

What this trial tests

NA trial testing MAMP therapy with MARPE expander in Malocclusion, Angle Class III in 35 participants. Completed in 10 August 2019.

Timeline

9 June 2017

Primary endpoint
10 August 2019

10 August 2019

Quick facts

Lead sponsor	University of Sao Paulo
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	35
Start date	9 June 2017
Primary completion	10 August 2019
Estimated completion	10 August 2019
Sites	1 location across Brazil

Drugs / interventions tested

MAMP therapy with MARPE expander
MAMP therapy with Hyrax expander

Conditions studied

Malocclusion, Angle Class III — all drugs for Malocclusion, Angle Class III →
Crossbite (Anterior) (Posterior) — all drugs for Crossbite (Anterior) (Posterior) →

Sponsor

University of Sao Paulo

Who can join

Adults 9 to 13, any sex, with Malocclusion, Angle Class III or Crossbite (Anterior) (Posterior). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates the dentoskeletal effects produced by two maxillary protraction protocols in adolescent patients. Half of participants will be treated with a tooth-borne and tooth-bone-borne expanders as anchorage in the maxillary arch. Miniscrews will be used as anchorage in the mandibular arch for both groups.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Dentoskeletal comparison of miniscrew-anchored maxillary protraction with hybrid and conventional hyrax expanders: A randomized clinical trial.
Miranda F, Cunha Bastos JCD, Magno Dos Santos A, Janson G, et al · · 2021 · cited 17× · PMID 34509329 · DOI 10.1016/j.ajodo.2021.02.017
Upper airway changes in Class III patients using miniscrew-anchored maxillary protraction with hybrid and hyrax expanders: a randomized controlled trial.
Miranda F, Garib D, Pugliese F, da Cunha Bastos JC, et al · · 2022 · cited 6× · PMID 34041608 · DOI 10.1007/s00784-021-03989-3
Comparison of alveolar bone morphology after expansion with hybrid and conventional Hyrax expanders.
Silva I, Miranda F, Bastos JCDC, Garib D. · · 2024 · cited 2× · PMID 39229946 · DOI 10.2319/092623-650.1
Pain and discomfort perception during miniscrew-anchored maxillary protraction: secondary data analysis of a randomized clinical trial.
Miranda F, Parra LD, Bastos JCDC, Santos AMD, et al · · 2023 · PMID 36795039 · DOI 10.2319/092022-655.1

Verify or expand the search:

Other University of Sao Paulo trials

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03712007 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Sao Paulo
Last refreshed: 12 May 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03712007.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing