Last reviewed · How we verify
NCT03705091: TransRASL
MRI in Renal Transplantation
trial testing Magnetic resonance imaging in End Stage Renal Disease in 20 participants. Status unknown.
20 February 2019
Quick facts
| Lead sponsor | NHS Greater Glasgow and Clyde |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 11 April 2017 |
| Primary completion | 20 February 2019 |
| Estimated completion | 20 March 2019 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Magnetic resonance imaging
Conditions studied
- End Stage Renal Disease — all drugs for End Stage Renal Disease →
- Renal Transplant Rejection — all drugs for Renal Transplant Rejection →
- Kidney Transplant Failure and Rejection — all drugs for Kidney Transplant Failure and Rejection →
- Chronic Kidney Diseases — all drugs for Chronic Kidney Diseases →
Sponsor
NHS Greater Glasgow and Clyde — full company profile →
Who can join
Adults 18 to 80, any sex, with End Stage Renal Disease or Renal Transplant Rejection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Renal transplantation is the optimal method of treatment for end stage kidney disease however median lifespan of a kidney transplant is around 15 years. Existing methods of measuring transplant function and structure from blood and urine markers are imperfect; renal biopsy is often performed but is invasive. Novel methods of investigating transplant function are therefore required and emerging renal MRI sequences including ASL and diffusion weighted imaging may yield helpful biomarkers. Investigators will recruit 20 patients in the first year after transplant and measure MRI biomarkers at three time points, with correlation to existing methods of measuring transplant function.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients.
Rankin AJ, Allwood-Spiers S, Lee MMY, Zhu L, et al · · 2020 · cited 10× · PMID 31823275 · DOI 10.1007/s10334-019-00809-4
Verify or expand the search:
- PubMed search for NCT03705091
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03705091 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by NHS Greater Glasgow and Clyde
- Last refreshed: 15 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03705091.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing