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NCT03703934
Central Pain Mechanisms in Patients With Hand-Osteoarthritis, Psoriatic Arthritis and Healthy Controls
trial in Arthritis, Psoriatic in 180 participants. Suspended.
1 April 2021
Quick facts
| Lead sponsor | Aalborg University Hospital |
|---|---|
| Status | Suspended |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 20 October 2018 |
| Primary completion | 1 April 2021 |
| Estimated completion | 30 July 2021 |
| Sites | 1 location across Denmark |
Conditions studied
- Arthritis, Psoriatic — all drugs for Arthritis, Psoriatic →
- Hand Osteoarthritis — all drugs for Hand Osteoarthritis →
Sponsor
Aalborg University Hospital
Who can join
18 and older, any sex, with Arthritis, Psoriatic or Hand Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this trial different parts of the pain signalling system involved in two rheumatic diseases - painful hand osteoarthritis and psoriatic arthritis, is examined. These measurements will be compared to those of healthy volunteers The hypothesis is that patients with hand osteoarthritis and psoriatic arthritis react differently to painful and non-painful stimuli compared with the healthy volunteers. The aim is to recruit 66 patients with painful hand-osteoarthritis, 66 patients with painful psoriatic arthritis and 66 healthy subjects not currently suffering from any pain conditions. After completing an informed consent form subjects will participate in a single clinical visit. The pain signalling system is examined using pressure algometry and cuff algometry. A pressure algometer is a pistol shaped device that elicits pressure through a rod and a cuff algometer is akin to a blood pressure cuff. Different thresholds will be measured, such as when the sensation of pressure becomes painful and when the painful pressure becomes unbearable. Participants will also get hand strength tested, have their joints examined and answer questionnaires regarding daily function and quality of life. Furthermore participants will get blood drawn which is analysed for the presence of markers of inflammation and joint degeneration.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
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Other Aalborg University Hospital trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03703934 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aalborg University Hospital
- Last refreshed: 5 January 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03703934.
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