NCT03702452 is a NA clinical trial of functional rehabilitation nursing program in Acute Ischemic Stroke, sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

Who is sponsoring NCT03702452?

NCT03702452 is sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

What drugs are being tested in NCT03702452?

Interventions in NCT03702452: functional rehabilitation nursing program, control group.

What condition does NCT03702452 study?

NCT03702452 studies Acute Ischemic Stroke.

Is NCT03702452 still recruiting?

NCT03702452 is currently status unknown. Last updated 12 February 2020.

Last reviewed 2020-02-12 · How we verify

NCT03702452

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke

Status unknown NA Last updated 12 February 2020

What this trial tests

NA trial testing functional rehabilitation nursing program in Acute Ischemic Stroke in 212 participants. Status unknown.

Timeline

21 November 2018

Primary endpoint
31 December 2020

31 December 2021

Quick facts

Lead sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	212
Start date	21 November 2018
Primary completion	31 December 2020
Estimated completion	31 December 2021
Sites	1 location across China

Drugs / interventions tested

functional rehabilitation nursing program
control group — full drug profile →

Conditions studied

Acute Ischemic Stroke — all drugs for Acute Ischemic Stroke →

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Who can join

Adults 18 to 90, any sex, with Acute Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment. Motor rehabilitation in acute phase is beneficial for improving patient's structure and function of corticospinal tract. However, it is difficult to obtain effective rehabilitation during the acute phase of stroke because of the insufficiency of professional rehabilitation therapists in stroke wards in China.The present study is to verify that nursing-directed rehabilitation can compensate for the shortage of professional rehabilitation therapists. Our previous study indicated that nursing-directed motor function rehabilitation provided more obvious effect on stroke patients with a weighted corticospinal tract lesion load (wCST-LL) smaller than 2ml. We assume that implementing rehabilitation nursing based on the wCST-LL can realize nursing-directed, wCST-LL-based precision motor rehabilitation during acute phase of ischemic stroke.The present study is to conduct randomized clinical trial to confirm the effect of nursing-directed precision rehabilitation for motor function in acute stroke patients grouped by wCST-LL, and to evaluate the effect of this precision rehabilitation by using functional scale, and to explore the histopathologic mechanism of the precision rehabilitation nursing by mean of neuroelectrophysiology and neuroimaging examination. This study might provide theoretical support for motor rehabilitation in patients during acute phase of stroke.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

Activities of daily living measurement after ischemic stroke: Rasch analysis of the modified Barthel Index.
Yang H, Chen Y, Wang J, Wei H, et al · · 2021 · cited 37× · PMID 33655956 · DOI 10.1097/md.0000000000024926
Physical rehabilitation approaches for the recovery of function and mobility following stroke.
Todhunter-Brown A, Sellers CE, Baer GD, Choo PL, et al · · 2025 · cited 16× · PMID 39932103 · DOI 10.1002/14651858.cd001920.pub4
The controlling nutritional status score and risk factors associated with malnutrition in patients with acute ischemic stroke.
Chen Y, Yang H, Lan M, Wei H, et al · · 2023 · cited 12× · PMID 36970524 · DOI 10.3389/fneur.2023.1067706
Effectiveness of Rehabilitation Nursing versus Usual Therapist-Led Treatment in Patients with Acute Ischemic Stroke: A Randomized Non-Inferiority Trial.
Wang J, Zhang Y, Chen Y, Li M, et al · · 2021 · cited 12× · PMID 34188460 · DOI 10.2147/cia.s306255
Rehabilitation nursing for motor functional recovery of acute ischaemic stroke: study protocol for a randomised controlled trial.
Wang J, Chen Y, Zhang Y, Li M, et al · · 2020 · cited 7× · PMID 32978194 · DOI 10.1136/bmjopen-2020-037391
Whether perceived limb heaviness affects return to work among patients with ischemic stroke.
Chen Y, Yang H, Chen Y, Wei H, et al · · 2024 · cited 1× · PMID 39686446 · DOI 10.1097/md.0000000000040466
Limb heaviness as a sensorimotor disorder alters rehabilitation adherence after a stroke.
Chen Y, Yang H, Chen Y, Wei H, et al · · 2022 · cited 1× · PMID 36061991 · DOI 10.3389/fneur.2022.840808

Verify or expand the search:

Other recruiting trials for Acute Ischemic Stroke

Currently open trials in the same condition.

NCT07115940 — Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours · NA · recruiting
NCT07404852 — Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemi · NA · recruiting
NCT07361302 — A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Pe · Phase 3 · recruiting
NCT07436156 — SUMMIT RISE Study of Acute Ischemic Stroke Patients · Phase 4 · recruiting
NCT07203625 — Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours · Phase 4 · recruiting

Other Second Affiliated Hospital, School of Medicine, Zhejiang University trials

Trials by the same sponsor.

NCT07445152 — Research on Construction and Verification of Multimodal Medical Imaging Large Model · not yet recruiting
NCT06775665 — A Real-World Study on Hypertrophic Cardiomyopathy in Chinese Population · not yet recruiting
NCT07533422 — Rescue Reatment of Helicobacter Pylori Based on Fecal Antimicrobial Resistance Gene Testing · NA · not yet recruiting
NCT07487285 — A Non-inferiority Study of Laser Combined With Ultrasonic Debridement Therapy (LCUDT) Versus Manual Combined With Ultras · NA · not yet recruiting
NCT07505186 — Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell Carcinoma · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03702452 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Second Affiliated Hospital, School of Medicine, Zhejiang University
Last refreshed: 12 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03702452.

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