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NCT03700788
2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
Phase 3 trial testing Chlorhexidine in Apical Periodontitis in 40 participants. Status unknown.
30 June 2025
Quick facts
| Lead sponsor | University of Southern California |
|---|---|
| Phase | Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 30 May 2023 |
| Primary completion | 30 June 2025 |
| Estimated completion | 31 August 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Chlorhexidine (CHLORHEXIDINE) — full drug profile →
- Calcium Hydroxide — full drug profile →
Conditions studied
- Apical Periodontitis — all drugs for Apical Periodontitis →
Sponsor
University of Southern California
Who can join
Adults 18 to 80, any sex, with Apical Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a Pilot Phase III single-blind randomized controlled clinical trial in patients, aged 18 years and older, presenting with symptoms of apical periodontitis. The overall goal is to assess whether 2% Chlorhexidine (CHX) is superior to Calcium Hydroxide in reducing interappointment pain.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03700788
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Apical Periodontitis
Currently open trials in the same condition.
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Other University of Southern California trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03700788 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Southern California
- Last refreshed: 8 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03700788.
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