NCT03699930 is a NA clinical trial of tDCS in Stroke, sponsored by Casa Colina Hospital and Centers for Healthcare.

Who is sponsoring NCT03699930?

NCT03699930 is sponsored by Casa Colina Hospital and Centers for Healthcare.

What drugs are being tested in NCT03699930?

Interventions in NCT03699930: tDCS, Speech and language therapy.

What condition does NCT03699930 study?

NCT03699930 studies Stroke, Aphasia.

Is NCT03699930 still recruiting?

NCT03699930 is currently completed. Last updated 7 July 2023.

Last reviewed 2023-07-07 · How we verify

NCT03699930

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Neuromodulation on Language Impairments in Stroke Patients

Completed NA Last updated 7 July 2023

What this trial tests

NA trial testing tDCS in Stroke in 24 participants. Completed in 1 January 2023.

Timeline

1 January 2018

Primary endpoint
1 September 2022

1 January 2023

Quick facts

Lead sponsor	Casa Colina Hospital and Centers for Healthcare
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	24
Start date	1 January 2018
Primary completion	1 September 2022
Estimated completion	1 January 2023
Sites	1 location across United States

Drugs / interventions tested

tDCS — full drug profile →
Speech and language therapy

Conditions studied

Stroke — all drugs for Stroke →
Aphasia — all drugs for Aphasia →

Sponsor

Casa Colina Hospital and Centers for Healthcare

Who can join

Adults 18 to 85, any sex, with Stroke or Aphasia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Up to 40% of stroke survivors suffer from aphasia, making recovery of language abilities a top priority in stroke rehabilitation. Conventional speech and language therapy may have limited effectiveness. Leveraging multimodal data (behavioral, neuroimaging, and genetics), this study aims to 1) evaluate the efficacy of combining tDCS with speech therapy, 2) examine neural changes associated with recovery, 3) identify factors influencing response to treatment.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Cerebellar transcranial direct current stimulation improves quality of life in individuals with chronic poststroke aphasia.
Zheng ZS, Wang J, Lee S, Wang KX, et al · · 2025 · cited 6× · PMID 40011597 · DOI 10.1038/s41598-025-90927-y
Impact of neuromodulation on post-stroke aphasia: a multimodal randomized controlled study
Zheng ZS, Wang KX, Millan H, Lee S, et al · · 2023 · cited 1× · DOI 10.1101/2023.02.12.23285828
Cerebellar transcranial direct current stimulation improves quality of life in individuals with chronic post-stroke aphasia
Zheng ZS, Wang J, Lee S, Wang KX, et al · · 2024 · DOI 10.21203/rs.3.rs-4708028/v1

Verify or expand the search:

Other trials of tDCS

Trials testing the same drug.

NCT07400939 — Brain Stimulation Combined With Watching Hand Movements to Improve Hand Recovery in Chronic Stroke · NA · recruiting
NCT06994390 — Neuropathic Pain Intervention With tDCS in Brazilian Military Personnel (NeuBRAIN Trial) · NA · not yet recruiting
NCT07358832 — Neuromodulation Through Multisensory Stimulation for Visual Field Deficits in the Subacute Stage of Disease · NA · recruiting
NCT07331779 — Effect of tDCS Timing on Motor Recovery in Acute Stroke Rehabilitation · NA · not yet recruiting
NCT06972368 — Home-Based tDCS for Depression in BPD · NA · recruiting

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07356011 — Exoskeleton for Balance · NA · recruiting
NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other Casa Colina Hospital and Centers for Healthcare trials

Trials by the same sponsor.

NCT07535788 — Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting · not yet recruiting
NCT07492602 — Comparison of Gait Metrics in Patients With Stroke, Traumatic Brain Injury, and Multiple Sclerosis · NA · not yet recruiting
NCT06226493 — EEG Changes and DNA Markers Related to taVNS in Stroke Patients: a Preliminary Study · NA · recruiting
NCT05945784 — Exploring Accessible Beauty for Individuals With Upper Extremity Deficits · completed
NCT05225220 — Multimodal Investigation of Post COVID-19 in Females · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03699930 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Casa Colina Hospital and Centers for Healthcare
Last refreshed: 7 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03699930.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing