NSAIDs vs. Coxibs in the Presence of Aspirin

NCT03699293 PHASE4 RECRUITING

The objectives of this single site, randomized, crossover study is to evaluate the pharmacodynamic interactions between aspirin, NSAIDs and Coxibs with respect to platelet function, biomarkers of inflammation and endothelial function.

Details

Lead sponsor	Inova Health Care Services
Phase	PHASE4
Status	RECRUITING
Enrolment	30
Start date	Sat Sep 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sun Nov 24 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Rheumatoid Arthritis
• Cardiovascular Diseases

Interventions

• celecoxib 200mg capsule
• naproxen sodium 550mg tablet
• Aspirin 81mg tablet

Countries

United States