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NCT03694067

Androgenetic Alopecia and the JAK-STAT Pathway

Completed Last updated 28 January 2020
What this trial tests

trial testing Punch skin biopsy in Androgenetic Alopecia in 25 participants. Completed in 1 December 2019.

Timeline
15 October 2018
Primary endpoint
1 December 2019
1 December 2019

Quick facts

Lead sponsorCairo University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment25
Start date15 October 2018
Primary completion1 December 2019
Estimated completion1 December 2019
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Cairo University

Who can join

18 and older, male only, with Androgenetic Alopecia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is a well known fact that the JAK-STAT pathway plays a pivotal role in the pathogenesis of alopecia areata. Both phosphorylated STAT 1 and 3 have been found to be upregulated in the disease. However, whether this pathway plays a role in other hair loss disorders remains unclear. The study aims at assessing STAT3 levels in male patients with androgenetic alopecia. The investigators hypothesize that STAT3 levels will be elevated (due to a previous study proving that JAK-STAT pathway is involved in non-immune mediated hair loss in mice.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other trials of Punch skin biopsy

Trials testing the same drug.

Other recruiting trials for Androgenetic Alopecia

Currently open trials in the same condition.

Other Cairo University trials

Trials by the same sponsor.

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