Last reviewed · How we verify
MSG Use With 18F-DCFPyL PET/CT Imaging
18F-DCFPyL is an agent that binds to prostate specific membrane antigen (PSMA). Due to high levels of PSMA in prostate cancer, treatments targeting PSMA have been developed to deliver therapy to these specific target cells. Unfortunately when this treatment is delivered there is radiotracer uptake in the salivary glands and kidneys, not related to cancer, which causes dry mouth and causes patients to stop treatment. It is proposed that having tomato juice containing monosodium glutamate (MSG) may reduce radiotracer uptake in the salivary glands and kidneys and reduce damage to these tissues.
Details
| Lead sponsor | British Columbia Cancer Agency |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 10 |
| Start date | Mon Nov 04 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Fri May 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Prostate Cancer
- Prostate Cancer Metastatic
- Prostatic Neoplasm
Interventions
- 18F-DCFPyL PET/CT scan
- Placebo drink
- MSG drink
Countries
Canada