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NCT03692546
Liposomal Bupivacaine for Pain Control After Rotator Cuff Repair
NA trial testing Liposomal bupivacaine (LB) in Rotator Cuff Tear in 50 participants. Completed in 1 September 2018.
1 March 2018
Quick facts
| Lead sponsor | Orthopaedic & Neurosurgery Specialists |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 50 |
| Start date | 1 February 2017 |
| Primary completion | 1 March 2018 |
| Estimated completion | 1 September 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Liposomal bupivacaine (LB) — full drug profile →
Conditions studied
- Rotator Cuff Tear — all drugs for Rotator Cuff Tear →
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
Orthopaedic & Neurosurgery Specialists
Who can join
18 and older, any sex, with Rotator Cuff Tear or Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The use of an interscalene block (ISB) is often associated with rebound pain that could be avoided through adjunctive therapy with longer duration. Administration of a liposomal bupivacaine (LB) field block in addition to ISB would overcome this rebound pain to provide greater pain relief and reduce opiate consumption when compared to ISB alone. 50 patients were recruited and randomized into groups that either received or did not receive an intraoperative LB field block in addition to standard ISB administration. Visual Analog Scale (VAS) pain scores and narcotic consumption were recorded over the five-day postoperative period to determine the effectiveness of LB pain relief.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03692546
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Liposomal bupivacaine (LB)
Trials testing the same drug.
- NCT07509866 — Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal · NA · recruiting
- NCT06806410 — The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery · Phase 4 · active not recruiting
- NCT04393207 — TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery · Phase 4 · terminated
Other recruiting trials for Rotator Cuff Tear
Currently open trials in the same condition.
- NCT07412184 — Research and Clinical Validation of a Wearable Device-Based Remote Rehabilitation System for Postoperative Rotator Cuff · NA · recruiting
- NCT06918041 — FiberLocker® System Augmentation of Rotator Cuff Repairs · NA · recruiting
- NCT07005063 — Rotator Cuff Tendon Repair With FiberLocker System Patch Augmentation · NA · recruiting
- NCT06878391 — ISB With SSNB & ANB · NA · recruiting
- NCT06766630 — Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement · Phase 2, PHASE3 · recruiting
Other Orthopaedic & Neurosurgery Specialists trials
Trials by the same sponsor.
- NCT03728946 — Interscalene Block With and Without Liposomal Bupivacaine in Shoulder Surgery · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03692546 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Orthopaedic & Neurosurgery Specialists
- Last refreshed: 2 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03692546.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing