Last reviewed · How we verify
NCT03691792
Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy
NA trial testing Cognitive-Behavioral Therapy (CBT-SAD) in Seasonal Affective Disorder in 141 participants. Completed in 28 February 2025.
28 February 2025
Quick facts
| Lead sponsor | University of Vermont |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 141 |
| Start date | 1 September 2018 |
| Primary completion | 28 February 2025 |
| Estimated completion | 28 February 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cognitive-Behavioral Therapy (CBT-SAD)
- Light Therapy
Conditions studied
- Seasonal Affective Disorder — all drugs for Seasonal Affective Disorder →
Sponsor
University of Vermont
Who can join
18 and older, any sex, with Seasonal Affective Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Major depression is a highly prevalent, chronic, and debilitating mental health problem with significant social cost that poses a tremendous economic burden. Winter seasonal affective disorder (SAD) is a subtype of recurrent major depression that affects 5% of the population (14.5 million Americans), involving substantial depressive symptoms for about 5 months of each year during most years, beginning in young adulthood.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Elucidating treatment targets and mediators within a confirmatory efficacy trial: study protocol for a randomized controlled trial of cognitive-behavioral therapy vs. light therapy for winter depression.
Rohan KJ, Franzen PL, Roeckelin KA, Siegle GJ, et al · · 2022 · cited 1× · PMID 35550645 · DOI 10.1186/s13063-022-06330-9 -
Elucidating Treatment Targets and Mediators within a Confirmatory Efficacy Trial: Study Protocol for a Randomized Controlled Trial of Cognitive-Behavioral Therapy vs. Light Therapy for Winter Depression
Rohan KJ, Franzen PL, Roecklein KA, Siegle GJ, et al · · 2022 · DOI 10.21203/rs.3.rs-1359973/v1
Verify or expand the search:
- PubMed search for NCT03691792
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03691792 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Vermont
- Last refreshed: 3 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03691792.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing