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NCT03691350
Bronchoscopy in Determining the Effect of E-Cigarette Smoking on Biomarkers in the Lungs
EARLY_PHASE1 trial testing Bronchoscopy with Bronchoalveolar Lavage in Cigarette Smoker in 239 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Ohio State University Comprehensive Cancer Center |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 239 |
| Start date | 17 September 2018 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Bronchoscopy with Bronchoalveolar Lavage
- Cigarette — full drug profile →
- Electronic Cigarette — full drug profile →
- Electronic Cigarette — full drug profile →
- Laboratory Biomarker Analysis — full drug profile →
- Nicotine Replacement — full drug profile →
- Questionnaire Administration
Conditions studied
- Cigarette Smoker — all drugs for Cigarette Smoker →
- Current Every Day Smoker — all drugs for Current Every Day Smoker →
Sponsor
Ohio State University Comprehensive Cancer Center
Who can join
Adults 21 to 52, any sex, with Cigarette Smoker or Current Every Day Smoker. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial studies biomarkers obtained by bronchoscopy (bronchoalveolar lavage and lung brushings) to determine the effect of smoking e-cigarettes on the lungs. Studying samples of lung cells from participants who smoke e-cigarettes may help doctors learn more about changes that occur in deoxyribonucleic acid and identify biomarkers related to cancer.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03691350
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bronchoscopy with Bronchoalveolar Lavage
Trials testing the same drug.
- NCT07064278 — Combined Diagnostic Approach for Refractory Mycoplasma Pneumonia in Children · NA · completed
- NCT04913311 — Predictive Biomarkers for Pneumonitis After Chemoradiotherapy and Immunotherapy in Patients With Non-small Cell Lung Can · recruiting
- NCT02937402 — Bronchoscopy With Bronchoalveolar Lavage in Identifying Biomarkers of Response to Immune Checkpoint Inhibitors in Patien · NA · terminated
Other recruiting trials for Cigarette Smoker
Currently open trials in the same condition.
- NCT03865472 — rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers · NA · active not recruiting
- NCT03199651 — Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer · NA · recruiting
- NCT02697227 — Behavioral Activation Therapy and Nicotine Replacement Therapy in Increasing Smoking Cessation · NA · active not recruiting
- NCT02271919 — Varenicline and Combined NRT for Smoking Cessation · Phase 4 · active not recruiting
Other Ohio State University Comprehensive Cancer Center trials
Trials by the same sponsor.
- NCT06816979 — Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell · NA · not yet recruiting
- NCT07529483 — Endoscopic Ultrasound-Guided Chemoablation for the Treatment of Pancreatic Cysts · Phase 2 · not yet recruiting
- NCT07455513 — A Novel Tobacco Cessation Resource for Smokers With a Diagnosed or Suspected Thoracic Cancer · NA · not yet recruiting
- NCT07217990 — Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer · Phase 1, PHASE2 · not yet recruiting
- NCT07503925 — THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03691350 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ohio State University Comprehensive Cancer Center
- Last refreshed: 10 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03691350.
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