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NCT03683537
Association Between Changes of GFAP After Surgery and Postoperative Delayed Cognitive Recovery
trial testing Glial fibrillary acidic protein in Astrogliosis in 30 participants. Completed in 15 December 2021.
15 November 2021
Quick facts
| Lead sponsor | Moscow Clinical Scientific Center |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 15 February 2018 |
| Primary completion | 15 November 2021 |
| Estimated completion | 15 December 2021 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- Glial fibrillary acidic protein
Conditions studied
- Astrogliosis — all drugs for Astrogliosis →
- Postoperative Cognitive Dysfunction — all drugs for Postoperative Cognitive Dysfunction →
- Postoperative Delirium — all drugs for Postoperative Delirium →
Sponsor
Moscow Clinical Scientific Center
Who can join
60 and older, any sex, with Astrogliosis or Postoperative Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Assessment of serum level of glial fibrillary acidic protein (GFAP) before surgery (on the day of surgery), 24 hours after surgery and on 3 or 4 postoperative day. Neuropsychological testing before surgery and on 3 or 4 day after surgery. Investigation of relationship between changes of GFAP and scores of neuropsychological tests.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03683537
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03683537 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Moscow Clinical Scientific Center
- Last refreshed: 9 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03683537.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing