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NCT03681847
Crystalloids Versus Colloids Versus Hypertonic Saline as a Co-load During Spinal Anesthesia.
NA trial testing Normal saline in Spinal Anaesthesia in 120 participants. Completed in 30 August 2018.
30 August 2018
Quick facts
| Lead sponsor | National Cancer Institute, Egypt |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 120 |
| Start date | 28 February 2018 |
| Primary completion | 30 August 2018 |
| Estimated completion | 30 August 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Normal saline
- hydroxyethyl starch — full drug profile →
- Hypertonic saline — full drug profile →
Conditions studied
- Spinal Anaesthesia — all drugs for Spinal Anaesthesia →
Sponsor
National Cancer Institute, Egypt
Who can join
Adults 18 to 65, any sex, with Spinal Anaesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Spinal anesthesia is commonly accompanied by hypotension due to vasodilation that follows sympathetic blockade and decreased systemic vascular resistance. Prevention of hypotension is usually achieved through administration of fluids and vasopressors .There is an ongoing debate concerning both the proper fluid timing, pre-load against co-load and fluid type crystalloids against colloids .This study aims at comparing the effectiveness of co-loading of crystalloids versus colloids versus hypertonic saline 3% in preventing hypotension induced by spinal anesthesia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03681847
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Spinal Anaesthesia
Currently open trials in the same condition.
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Other National Cancer Institute, Egypt trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03681847 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cancer Institute, Egypt
- Last refreshed: 24 September 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03681847.
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