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NCT03680794
Soluble Cluster of Differentiation 160 (sCD160) in Sera and Intra-ocular Fluids: Association With Ischaemic Retinopathies
NA trial testing sampling of ophthalmic liquid in Diabetic Retinopathy in 120 participants. Status unknown.
1 December 2024
Quick facts
| Lead sponsor | CHU de Reims |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 120 |
| Start date | 27 June 2018 |
| Primary completion | 1 December 2024 |
| Estimated completion | 1 February 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- sampling of ophthalmic liquid
Conditions studied
- Diabetic Retinopathy — all drugs for Diabetic Retinopathy →
- Retinal Vein Occlusion — all drugs for Retinal Vein Occlusion →
Sponsor
CHU de Reims — full company profile →
Who can join
18 and older, any sex, with Diabetic Retinopathy or Retinal Vein Occlusion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
CD160 represents a new angiogenic factor as its specific engagement by an agonist monoclonal antibody directed against human CD160 reduced angiogenesis of endothelial cells with a distinct mechanism from current angiogenic therapies that target the VEGF/VEGF-R pathway. A soluble form of CD160, sCD160, has been found to be highly expressed in the vitreous and the sera of patients with severe diabetic retinopathies, and can now be dosed with help of an ELISA test. The investigators aim to evaluate the association between ischaemic retinopathies (patients with or without) and sCD160 concentrations in the vitreous, the aqueous humour and the serum.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03680794
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03680794 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by CHU de Reims
- Last refreshed: 20 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03680794.
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