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NCT03679299
Vascular Implications of a Naturally Occurring Asthma Exacerbation
trial testing Observational - No intervention in Asthma in 3 participants. Terminated before completion.
30 June 2024
Quick facts
| Lead sponsor | University of Alberta |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 3 |
| Start date | 10 October 2018 |
| Primary completion | 30 June 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Observational - No intervention
Conditions studied
- Asthma — all drugs for Asthma →
- Inflammation — all drugs for Inflammation →
- Cardiovascular Risk Factor — all drugs for Cardiovascular Risk Factor →
Sponsor
University of Alberta
Who can join
Adults 18 to 55, any sex, with Asthma or Inflammation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics. Vascular dysfunction is seen in people at high risk of CVD and has been linked to inflammation. During an asthma attack, levels of inflammation in the whole body increase, which could potentially explain why asthmatics are at increased risk of CVD. In the proposed study the investigators will examine if asthma attacks lead to increased risk of CVD by evaluating inflammatory levels and vascular function directly following asthma attacks, 2 days and 14 days after discharge. The investigators will compare these results to non-asthmatics. The results from this study will help us understand why asthmatics are at increased risk of CVD.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03679299
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03679299 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alberta
- Last refreshed: 5 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03679299.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing