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NCT03678090
The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.
Phase 2 trial testing tPA standard dosage in Pleural Effusion. Withdrawn.
28 February 2020
Quick facts
| Lead sponsor | Yale University |
|---|---|
| Phase | Phase 2 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Start date | 1 December 2018 |
| Primary completion | 28 February 2020 |
| Estimated completion | 28 February 2020 |
Drugs / interventions tested
- tPA standard dosage — full drug profile →
- tPA low dosage — full drug profile →
Conditions studied
- Pleural Effusion — all drugs for Pleural Effusion →
- Cancer, Lung — all drugs for Cancer, Lung →
Sponsor
Yale University
Who can join
18 and older, any sex, with Pleural Effusion or Cancer, Lung. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The safety and efficacy of fibrinolysis in patients with an indwelling pleural catheter for multi-loculated malignant pleural effusion.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03678090
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT06892691 — Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions · NA · recruiting
- NCT06314620 — Normal Saline Flushing With And Without Heparin Lock In Maintaining Small Bore Intercostal Chest Catheter (ICC) Patency · NA · recruiting
Other Yale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03678090 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yale University
- Last refreshed: 5 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03678090.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing