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NCT03673618
Soluble Corn Fiber Supplementation for Asthma
Phase 2 trial testing Soluble Corn Fiber in Asthma in Children in 20 participants. Completed in 31 December 2021.
31 December 2021
Quick facts
| Lead sponsor | Phoenix Children's Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 September 2019 |
| Primary completion | 31 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Soluble Corn Fiber — full drug profile →
Conditions studied
- Asthma in Children — all drugs for Asthma in Children →
Sponsor
Phoenix Children's Hospital
Who can join
Adults 6 to 17, any sex, with Asthma in Children. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Studies of the importance of the human microbiome have demonstrated that microbial metabolites of fermentation of our dietary products (e.g. dietary fiber) have a multitude of health benefits. The investigators aim to determine whether supplementation of asthmatic children with soluble corn fiber alongside standard of care reduces airway inflammation driven by the gut microbial metabolites acetate, propionate, or butyrate (short chain fatty acids).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A randomized, double-blind, placebo-controlled trial of soluble corn fiber supplementation for children with asthma.
Rank MA, Barroso DL, Conn KA, Pecak M, et al · · 2025 · PMID 41647190 · DOI 10.3389/falgy.2025.1707834
Verify or expand the search:
- PubMed search for NCT03673618
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Soluble Corn Fiber
Trials testing the same drug.
- NCT05516641 — Prebiotics in Rectal Cancer · NA · unknown
- NCT05066425 — Soluble Corn Fiber for Promoting Executive Function Study · NA · unknown
Other recruiting trials for Asthma in Children
Currently open trials in the same condition.
- NCT06372249 — A Clinical Trial of Soluble Fiber for Asthma · Phase 2 · recruiting
- NCT07412769 — ASMact: Study on Management of Bronchial Asthma · recruiting
- NCT07138027 — SMART Implementation-Effectiveness Trial 2 · NA · recruiting
- NCT07137923 — SMART Implementation-Effectiveness Trial 1 · NA · recruiting
- NCT06851715 — Improving Quality of Life for Teenagers With Asthma · NA · recruiting
Other Phoenix Children's Hospital trials
Trials by the same sponsor.
- NCT06372249 — A Clinical Trial of Soluble Fiber for Asthma · Phase 2 · recruiting
- NCT05925075 — Point of Care Lung Ultrasound in Preterm Infants with Respiratory Distress · enrolling by invitation
- NCT05563610 — Oral Penicillin Challenge and Allergy De-labeling in Children · Phase 4 · terminated
- NCT04344652 — Photoscreening for Retinoblastoma · NA · withdrawn
- NCT04040452 — Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03673618 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Phoenix Children's Hospital
- Last refreshed: 31 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03673618.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing