Last reviewed · How we verify
NCT03672877
Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia
NA trial testing Intensive exercise in Spastic Diplegia in 60 participants. Currently enrolling.
31 March 2026
Quick facts
| Lead sponsor | University of Alberta |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 28 January 2019 |
| Primary completion | 31 March 2026 |
| Estimated completion | 31 March 2027 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Intensive exercise
Conditions studied
- Spastic Diplegia — all drugs for Spastic Diplegia →
- Periventricular Leukomalacia — all drugs for Periventricular Leukomalacia →
Sponsor
University of Alberta
Who can join
Adults 8 Months to 36 Months, any sex, with Spastic Diplegia or Periventricular Leukomalacia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomized controlled trial, comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of gross motor function in young children with spastic diplegia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Engaging the Lower Extremity via Active Therapy Early (ELEVATE) Is Feasible and May Improve Gross Motor Function in Children with Spastic Bilateral Cerebral Palsy: A Case Series.
Hurd CL, Livingstone D, Smith A, Yang JF. · · 2023 · PMID 38037582 · DOI 10.3138/ptc-2023-0005
Verify or expand the search:
- PubMed search for NCT03672877
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spastic Diplegia
Currently open trials in the same condition.
- NCT07438223 — Effect Of Brain Gym Exercises On Balance And Quality Of Life In Children With Spastic Diplegia · NA · recruiting
- NCT07289347 — Effect of a Light Stimulated Footsteps Pathway on Gait in Spastic Children · NA · active not recruiting
- NCT06270550 — Role of Dynamic Movement Intervention in Children with Spastic Diplegia · NA · recruiting
- NCT07433647 — Evaluation of Brain MRI Changes in Cerebral Palsy Patients · recruiting
Other University of Alberta trials
Trials by the same sponsor.
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- NCT06649604 — Reducing Pain From Retinal Laser With Vibrational Stimulation · NA · not yet recruiting
- NCT06824077 — Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle · EARLY_PHASE1 · not yet recruiting
- NCT06920914 — Effects of Minimally vs. Ultra-Processed Diets on Potassium (K) Handling in CKD · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03672877 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alberta
- Last refreshed: 27 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03672877.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing