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NCT03670706: Team-KP
Knee Pain Nurse Led Package of CareTrial
NA trial testing Exercise in Osteoarthritis, Knee in 1,806 participants. Completed in 5 July 2021.
5 July 2021
Quick facts
| Lead sponsor | University of Nottingham |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | other |
| Enrollment | 1,806 |
| Start date | 26 November 2018 |
| Primary completion | 5 July 2021 |
| Estimated completion | 5 July 2021 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Exercise
- analgesic optimisation
Conditions studied
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
- Pain, Joint — all drugs for Pain, Joint →
Sponsor
University of Nottingham
Who can join
40 and older, any sex, with Osteoarthritis, Knee or Pain, Joint. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
1. To develop a training package for nurse-led management of knee osteoarthritis (OA), incorporating information about OA and core non-pharmacologic and pharmacologic principles of management of OA as recommended in the National Institute for Clinical Excellence and Health (NICE) guidelines for management of OA 2. To evaluate fidelity of delivery of individual components of this complex package of care for knee pain 3. To assess the acceptability of the intervention by exploring participant satisfaction with nurse-led complex package of care of knee pain. 4. To explore and resolve possible challenges to delivery of individual components within a complex package 5. To examine the feasibility of a definitive cohort randomised controlled trial of nurse-led care versus usual care of knee pain in terms of recruitment rate, drop-out rate, reasons for dropping out and completeness of outcome data 6. To explore whether such a trial should provide analgesia before non-pharmacologic interventions or vice versa
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: a mixed methods study.
Nomikos PA, Hall M, Fuller A, Millar B, et al · · 2021 · cited 7× · PMID 34326044 · DOI 10.1136/bmjopen-2020-045242 -
East Midlands knee pain multiple randomised controlled trial cohort study: cohort establishment and feasibility study protocol.
Hall M, Fuller A, Nomikos PA, Millar B, et al · · 2020 · cited 5× · PMID 32912951 · DOI 10.1136/bmjopen-2020-037760 -
Feasibility of conducting a cohort randomized controlled trial assessing the effectiveness of a nurse-led package of care for knee pain.
Fuller A, Hall M, Nomikos PA, Millar B, et al · · 2024 · cited 1× · PMID 37610332 · DOI 10.1093/rheumatology/kead432
Verify or expand the search:
- PubMed search for NCT03670706
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Osteoarthritis, Knee
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03670706 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Nottingham
- Last refreshed: 21 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03670706.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing