NCT03667963 is a NA clinical trial of Glucose in Carbohydrate Intolerance, sponsored by University of Toronto.

Who is sponsoring NCT03667963?

NCT03667963 is sponsored by University of Toronto.

What drugs are being tested in NCT03667963?

Interventions in NCT03667963: Glucose, Glucose plus lactulose, Hot Rice, Cold Rice.

What condition does NCT03667963 study?

NCT03667963 studies Carbohydrate Intolerance.

Is NCT03667963 still recruiting?

NCT03667963 is currently completed. Last updated 11 January 2019.

Last reviewed 2019-01-11 · How we verify

NCT03667963

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Genetic Variation in Starch-digesting Enzymes on Digestibility and Glycemic Index of Cold and Hot Rice

Completed NA Last updated 11 January 2019

What this trial tests

NA trial testing Glucose in Carbohydrate Intolerance in 40 participants. Completed in 21 December 2018.

Timeline

29 August 2018

Primary endpoint
21 December 2018

21 December 2018

Quick facts

Lead sponsor	University of Toronto
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	factorial
Masking	double
Primary purpose	basic science
Enrollment	40
Start date	29 August 2018
Primary completion	21 December 2018
Estimated completion	21 December 2018
Sites	1 location across Canada

Drugs / interventions tested

Glucose — full drug profile →
Glucose plus lactulose
Hot Rice
Cold Rice

Conditions studied

Carbohydrate Intolerance — all drugs for Carbohydrate Intolerance →

Sponsor

University of Toronto

Who can join

Adults 18 to 75, any sex, with Carbohydrate Intolerance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates the effect of different methods of preparation (cooked and consumed hot vs cooked, cooled overnight and consumed cold) and variation in the activity of salivary amylase on the glycemic index and carbohydrate digestibility in healthy human subjects. The effect of genetic variation in small intestinal starch digesting enzymes on glycemic index and starch digestibility will also be assessed.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Neither low salivary amylase activity, cooling cooked white rice, nor single nucleotide polymorphisms in starch-digesting enzymes reduce glycemic index or starch digestibility: a randomized, crossover trial in healthy adults.
Wolever TMS, El-Sohemy A, Ezatagha A, Zurbau A, et al · · 2021 · cited 4× · PMID 34293081 · DOI 10.1093/ajcn/nqab228

Verify or expand the search:

Other trials of Glucose

Trials testing the same drug.

NCT06955130 — Lactate and Glycerol Contribution to Gluconeogenesis · NA · not yet recruiting
NCT06424106 — Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes · NA · recruiting
NCT06638190 — Influence of the Fruit Matrix on Glucose and Insulin Responses After the Intake of Orange Juice in Healthy Human Males · NA · completed
NCT06358716 — Glycaemic Index Determination in Oral Nutrition Supplements · NA · recruiting
NCT06373016 — Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder · NA · recruiting

Other University of Toronto trials

Trials by the same sponsor.

NCT07184255 — Animated Video Education for Retinal Surgery · NA · not yet recruiting
NCT07259434 — Time Restricted Eating in Survivors Trial 2.0 · NA · not yet recruiting
NCT07486050 — The Impact of Social Worker Referrals on Diabetes and Loneliness · NA · active not recruiting
NCT07268729 — Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders · not yet recruiting
NCT07317921 — Validating IAAO for Muscle Outcomes · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03667963 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Toronto
Last refreshed: 11 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03667963.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing