Last reviewed · How we verify
NCT03667495
The Relationship Between Postoperative Changes of Oral and Intestinal Flora and Prognosis
trial in Gut Microbiota in 100 participants. Status unknown.
1 November 2019
Quick facts
| Lead sponsor | First Affiliated Hospital of Harbin Medical University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 November 2017 |
| Primary completion | 1 November 2019 |
| Estimated completion | 1 March 2021 |
| Sites | 1 location across China |
Conditions studied
- Gut Microbiota — all drugs for Gut Microbiota →
- Oral Microbiota — all drugs for Oral Microbiota →
- Colorectal Cancer — all drugs for Colorectal Cancer →
Sponsor
First Affiliated Hospital of Harbin Medical University
Who can join
Adults 18 to 80, any sex, with Gut Microbiota or Oral Microbiota. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Specific oral microbiome has been found to contribute to the development of colorectal cancer. We speculate that specific oral microbiota related to colorectal cancer relapse after curative treatment. This study aim to discover if any difference of oral microbiota exist in patients who suffer from cancer relapse compared with patients who do not. Finally develop patient-centred programmes of surveillance protocols base on microbiota analysis.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Gut microbiota: impacts on gastrointestinal cancer immunotherapy.
Lau HCH, Sung JJ, Yu J. · · 2021 · cited 42× · PMID 33435800 · DOI 10.1080/19490976.2020.1869504 -
Gut Microbiota-Based Algorithms in the Prediction of Metachronous Adenoma in Colorectal Cancer Patients Following Surgery.
Liu Y, Geng R, Liu L, Jin X, et al · · 2020 · cited 12× · PMID 32595614 · DOI 10.3389/fmicb.2020.01106 -
Bidirectional effects of intestinal microbiota and antibiotics: a new strategy for colorectal cancer treatment and prevention.
Zhang W, Zhang J, Liu T, Xing J, et al · · 2022 · cited 10× · PMID 35661254 · DOI 10.1007/s00432-022-04081-3
Verify or expand the search:
- PubMed search for NCT03667495
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other First Affiliated Hospital of Harbin Medical University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03667495 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by First Affiliated Hospital of Harbin Medical University
- Last refreshed: 21 September 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03667495.
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