Last reviewed · How we verify
NCT03659825
Ketone Esters for Optimization of Cognitive Performance in Hypoxia
NA trial testing Ketone Ester in Hypoxia in 16 participants. Status unknown.
31 October 2018
Quick facts
| Lead sponsor | HVMN Inc |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 16 |
| Start date | 1 September 2018 |
| Primary completion | 31 October 2018 |
| Estimated completion | 15 November 2018 |
Drugs / interventions tested
- Ketone Ester
- Taste Matched Placebo
- Hypoxic exposure
Conditions studied
Sponsor
HVMN Inc
Who can join
Adults 18 to 45, male only, with Hypoxia or Ketosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will investigate the effects of ketone ester drinks on cognitive performance in hypoxia.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives.
Poff AM, Rho JM, D'Agostino DP. · · 2019 · cited 52× · PMID 31680801 · DOI 10.3389/fnins.2019.01041 -
From bedside to battlefield: intersection of ketone body mechanisms in geroscience with military resilience.
Stubbs BJ, Koutnik AP, Volek JS, Newman JC. · · 2021 · cited 14× · PMID 33006708 · DOI 10.1007/s11357-020-00277-y
Verify or expand the search:
- PubMed search for NCT03659825
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ketone Ester
Trials testing the same drug.
- NCT06318299 — Effects of Exogenous Ketone Ester Supplementation on 3-hydroxybutyrate Concentrations in Human Cerebrospinal Fluid · NA · completed
- NCT05888506 — Ketone Ester Supplementation and Nocturnal Blood Pressure · NA · completed
- NCT03729934 — Ketones Supplementation and Postprandial Lipemia · NA · withdrawn
Other recruiting trials for Hypoxia
Currently open trials in the same condition.
- NCT07479511 — Adaptation of Lung Transplant Recipients at Extreme Altitude · active not recruiting
- NCT07287293 — Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia · NA · recruiting
- NCT07389083 — The Efficacy and Safety of the Supraglottic Oxygenation Via Nasotracheal Intubation for Deep Sedation Fiberoptic Broncho · NA · recruiting
- NCT07307560 — High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients · NA · recruiting
- NCT07408388 — Pulse Oximeter Accuracy During Stable Hypoxia Plateaus · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03659825 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by HVMN Inc
- Last refreshed: 6 September 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03659825.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing