NCT03659747 is a NA clinical trial of Probiotic in Gastrointestinal Symptoms, sponsored by Danisco.

Who is sponsoring NCT03659747?

NCT03659747 is sponsored by Danisco.

What drugs are being tested in NCT03659747?

Interventions in NCT03659747: Probiotic, Lactrase, Placebo.

What condition does NCT03659747 study?

NCT03659747 studies Gastrointestinal Symptoms, Breath Test.

Is NCT03659747 still recruiting?

NCT03659747 is currently completed. Last updated 5 March 2019.

Last reviewed 2019-03-05 · How we verify

NCT03659747

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Fat-free Milk

Completed NA Last updated 5 March 2019

What this trial tests

NA trial testing Probiotic in Gastrointestinal Symptoms in 34 participants. Completed in 21 December 2018.

Timeline

11 September 2018

Primary endpoint
21 December 2018

21 December 2018

Quick facts

Lead sponsor	Danisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	prevention
Enrollment	34
Start date	11 September 2018
Primary completion	21 December 2018
Estimated completion	21 December 2018
Sites	1 location across Germany

Drugs / interventions tested

Probiotic
Lactrase
Placebo

Conditions studied

Gastrointestinal Symptoms — all drugs for Gastrointestinal Symptoms →
Breath Test — all drugs for Breath Test →

Sponsor

Danisco — full company profile →

Who can join

Adults 25 to 60, any sex, with Gastrointestinal Symptoms or Breath Test. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of the study is to investigate the effect of probiotic supplementation on lactose maldigestion.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials.
Rasinkangas P, Forssten SD, Marttinen M, Ibarra A, et al · · 2022 · cited 7× · PMID 36149331 · DOI 10.1093/ajcn/nqac264

Verify or expand the search:

Other trials of Probiotic

Trials testing the same drug.

NCT07529457 — Akk09 in Adults With Constipation · NA · not yet recruiting
NCT07507955 — Probiotics for Constipation Relief in Adults · NA · not yet recruiting
NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07511855 — Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term T · Phase 2 · not yet recruiting
NCT07474064 — Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBC · Phase 2 · not yet recruiting

Other recruiting trials for Gastrointestinal Symptoms

Currently open trials in the same condition.

NCT07421596 — An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System · NA · recruiting
NCT07388264 — Impact of Weizmannia (Bacillus) Coagulans JBI-YZ6.3 on Gut Health and Fecal Microbiome Changes · NA · recruiting
NCT05972291 — Mechanisms of Gulf War Illness · NA · recruiting

Other Danisco trials

Trials by the same sponsor.

NCT05150184 — Isolation and Characterization of Multiple Microbial Species From Diverse Healthy Adults · completed
NCT04231162 — Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation · NA · completed
NCT04125810 — A Study to Assess the Safety and Efficacy of Probiotic to Modulate Psychological Stress · Phase 2 · completed
NCT03814668 — Effect of Probiotic Supplementation on Lactose Maldigestion Induced by Lactose Solution · NA · completed
NCT03187457 — PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?" · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03659747 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Danisco
Last refreshed: 5 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03659747.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing