NCT03658681 is a NA clinical trial of Saturated fat 14.9 E% in Postprandial Blood Glucose, sponsored by Oslo Metropolitan University.

Who is sponsoring NCT03658681?

NCT03658681 is sponsored by Oslo Metropolitan University.

What drugs are being tested in NCT03658681?

Interventions in NCT03658681: Saturated fat 14.9 E%, Polyunsaturated fat 13.6 E%.

What condition does NCT03658681 study?

NCT03658681 studies Postprandial Blood Glucose, Gut Microbiota, Satiety.

Is NCT03658681 still recruiting?

NCT03658681 is currently completed. Last updated 7 May 2020.

Last reviewed 2020-05-07 · How we verify

NCT03658681

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Fat Quality on Glycemic Regulation and Gut Microbiota After a Short-time Intervention in Healthy Individuals

Completed NA Last updated 7 May 2020

What this trial tests

NA trial testing Saturated fat 14.9 E% in Postprandial Blood Glucose in 20 participants. Completed in 31 December 2019.

Timeline

13 March 2018

Primary endpoint
31 January 2019

31 December 2019

Quick facts

Lead sponsor	Oslo Metropolitan University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	basic science
Enrollment	20
Start date	13 March 2018
Primary completion	31 January 2019
Estimated completion	31 December 2019
Sites	1 location across Norway

Drugs / interventions tested

Saturated fat 14.9 E%
Polyunsaturated fat 13.6 E%

Conditions studied

Postprandial Blood Glucose — all drugs for Postprandial Blood Glucose →
Gut Microbiota — all drugs for Gut Microbiota →
Satiety — all drugs for Satiety →

Sponsor

Oslo Metropolitan University

Who can join

Adults 18 to 65, any sex, with Postprandial Blood Glucose or Gut Microbiota. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall aim is to investigate effects of saturated versus polyunsaturated fat on glycemic regulation and satiety in a postprandial study with healthy individuals. The potential effects will be related to changes in gut microbiota, the circulating levels of short chain fatty acids, inflammation and gene expression in peripheral mononuclear blood cells.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Replacing saturated fatty acids with polyunsaturated fatty acids increases the abundance of Lachnospiraceae and is associated with reduced total cholesterol levels-a randomized controlled trial in healthy individuals.
Telle-Hansen VH, Gaundal L, Bastani N, Rud I, et al · · 2022 · cited 25× · PMID 36163070 · DOI 10.1186/s12944-022-01702-1
Gut microbiota is associated with dietary intake and metabolic markers in healthy individuals.
Gaundal L, Myhrstad MCW, Rud I, Gjøvaag T, et al · · 2022 · cited 22× · PMID 35844956 · DOI 10.29219/fnr.v66.8580
Beneficial effect on serum cholesterol levels, but not glycaemic regulation, after replacing SFA with PUFA for 3 d: a randomised crossover trial.
Gaundal L, Myhrstad MCW, Leder L, Byfuglien MG, et al · · 2021 · cited 14× · PMID 32873354 · DOI 10.1017/s0007114520003402
Gut microbiota, physical activity and/or metabolic markers in healthy individuals - towards new biomarkers of health.
Myhrstad MCW, Ruud E, Gaundal L, Gjøvaag T, et al · · 2024 · PMID 39668899 · DOI 10.3389/fnut.2024.1438876

Verify or expand the search:

Other Oslo Metropolitan University trials

Trials by the same sponsor.

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NCT06117098 — Mobile App for Risk Reduction of Type 2 Diabetes · NA · unknown
NCT05697120 — Long-term Effects of Individualized Follow-up With an App for One Year · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03658681 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Oslo Metropolitan University
Last refreshed: 7 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03658681.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing