NCT03658265 is a NA clinical trial of 7 days SIE plus 4 weeks PRE in Shoulder Dysfunction, sponsored by Wuhan University.

Who is sponsoring NCT03658265?

NCT03658265 is sponsored by Wuhan University.

What drugs are being tested in NCT03658265?

Interventions in NCT03658265: 7 days SIE plus 4 weeks PRE, 7 days SIE plus 3 weeks PRE, 3 days SIE plus 4 weeks PRE, 3 days SIE plus 3 weeks PRE.

What condition does NCT03658265 study?

NCT03658265 studies Shoulder Dysfunction, Breast Cancer, Modified Radical Mastectomy.

Is NCT03658265 still recruiting?

NCT03658265 is currently completed. Last updated 8 October 2020.

Last reviewed 2020-10-08 · How we verify

NCT03658265

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Exercise Training at Different Timeline on Shoulder Dysfunction After Breast Cancer Modified Radical Mastectomy

Completed NA Last updated 8 October 2020

What this trial tests

NA trial testing 7 days SIE plus 4 weeks PRE in Shoulder Dysfunction in 200 participants. Completed in 31 May 2020.

Timeline

10 September 2018

Primary endpoint
31 May 2020

31 May 2020

Quick facts

Lead sponsor	Wuhan University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	200
Start date	10 September 2018
Primary completion	31 May 2020
Estimated completion	31 May 2020
Sites	1 location across China

Drugs / interventions tested

7 days SIE plus 4 weeks PRE
7 days SIE plus 3 weeks PRE
3 days SIE plus 4 weeks PRE
3 days SIE plus 3 weeks PRE

Conditions studied

Shoulder Dysfunction — all drugs for Shoulder Dysfunction →
Breast Cancer — all drugs for Breast Cancer →
Modified Radical Mastectomy — all drugs for Modified Radical Mastectomy →

Sponsor

Wuhan University

Who can join

Adults 25 to 75, female only, with Shoulder Dysfunction or Breast Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients who underwent modified radical mastectomy were enrolled in the study. 200 subjects were randomly divided into 4 groups: 7 days postoperative shoulder isotonic training + 4 weeks postoperative progressive resistance training group, postoperative 7 Isometric training for the shoulder joint + progressive resistance training for 3 weeks after surgery group, 3 days postoperative isotope training + 4 weeks postoperative progressive resistance training group, 3 days postoperative shoulder isotonic training + postoperative 3 Weekly progressive resistance training group. The effects of interventional rehabilitation at different time points on the recovery of shoulder function after breast cancer operation were observed. The results of the study will provide evidence-based evidence for the time point of intervention in early functional exercise after modified radical mastectomy for breast cancer.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Physical Activity as an Imperative Support in Breast Cancer Management.
Ortega MA, Fraile-Martínez O, García-Montero C, Pekarek L, et al · · 2020 · cited 34× · PMID 33379177 · DOI 10.3390/cancers13010055
Advances in Diet and Physical Activity in Breast Cancer Prevention and Treatment.
Khalifa A, Guijarro A, Nencioni A. · · 2024 · cited 17× · PMID 39064705 · DOI 10.3390/nu16142262
Effect of different rehabilitation training timelines to prevent shoulder dysfunction among postoperative breast cancer patients: study protocol for a randomized controlled trial.
Shao YW, Shu Q, Xu D, Teng H, et al · · 2021 · cited 3× · PMID 33407753 · DOI 10.1186/s13063-020-04954-3

Verify or expand the search:

Other recruiting trials for Shoulder Dysfunction

Currently open trials in the same condition.

NCT07240129 — Effect of Graded Motor Imagery on Shoulder Dysfunction Post Mastectomy · NA · active not recruiting
NCT06886932 — Pain Education After Rotator Cuff Surgery · recruiting

Other Wuhan University trials

Trials by the same sponsor.

NCT07381946 — High-frequency Repetitive Transcranial Magnetic Stimulation for Patients With Dysphagia After Extubation · NA · active not recruiting
NCT06470178 — A Real-World Study of Neoadjuvant/Conversion Therapy for Colorectal Cancer With Chemotherapy And Anti-Angiogenic Targete · not yet recruiting
NCT06464601 — A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer · not yet recruiting
NCT06971705 — fMRI Study on Cerebral Localization and Network Mechanisms of rTMS in Chronic Ankle Instability Treatment · NA · active not recruiting
NCT06532994 — Predictive Algorithms for Critical Rehabilitation Outcomes · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03658265 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wuhan University
Last refreshed: 8 October 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03658265.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing