NCT03652948 is a Phase 2, PHASE3 clinical trial of Meru Health Ascend Program in Depression, sponsored by Palo Alto Veterans Institute for Research.

Who is sponsoring NCT03652948?

NCT03652948 is sponsored by Palo Alto Veterans Institute for Research.

What drugs are being tested in NCT03652948?

Interventions in NCT03652948: Meru Health Ascend Program.

What condition does NCT03652948 study?

NCT03652948 studies Depression, Depressive Symptoms.

Is NCT03652948 still recruiting?

NCT03652948 is currently completed. Last updated 10 March 2021.

Last reviewed 2021-03-10 · How we verify

NCT03652948

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Meru Health Ascend Mobile Intervention for Depression in Middle Aged and Older Adults

Completed Phase 2, PHASE3 Last updated 10 March 2021

What this trial tests

Phase 2, PHASE3 trial testing Meru Health Ascend Program in Depression in 70 participants. Completed in 15 January 2021.

Timeline

12 July 2018

Primary endpoint
15 January 2021

15 January 2021

Quick facts

Lead sponsor	Palo Alto Veterans Institute for Research
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	70
Start date	12 July 2018
Primary completion	15 January 2021
Estimated completion	15 January 2021
Sites	1 location across United States

Drugs / interventions tested

Meru Health Ascend Program

Conditions studied

Depression — all drugs for Depression →
Depressive Symptoms — all drugs for Depressive Symptoms →

Sponsor

Palo Alto Veterans Institute for Research

Who can join

Adults 40 to 120, any sex, with Depression or Depressive Symptoms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Using technology to deliver depression interventions is one way could alleviate the public health burden of depression. The study is testing a mobile app intervention program for depression that uses cognitive behavioral skills and mindfulness. This study seeks to obtain feedback on the intervention and refine the intervention and then test the intervention in a larger study. The mobile app intervention called the Meru Health Ascend program consists of the app and therapist support via messaging within the app.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effects of Mobile App-Based Intervention for Depression in Middle-Aged and Older Adults: Mixed Methods Feasibility Study.
Gould CE, Carlson C, Ma F, Forman-Hoffman V, et al · · 2021 · cited 19× · PMID 34185000 · DOI 10.2196/25808
Changes in Quality of Life and Loneliness Among Middle-Aged and Older Adults Participating in Therapist-Guided Digital Mental Health Intervention.
Gould CE, Carlson C, Alfaro AJ, Chick CF, et al · · 2021 · cited 15× · PMID 34957011 · DOI 10.3389/fpubh.2021.746904

Verify or expand the search:

Other recruiting trials for Depression

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NCT07449676 — Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression · NA · recruiting

Other Palo Alto Veterans Institute for Research trials

Trials by the same sponsor.

NCT07219251 — Engagement of Veterans With Lung Cancer · NA · recruiting
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NCT07069517 — Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD · NA · recruiting
NCT07303725 — Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology · recruiting
NCT07303712 — Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03652948 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Palo Alto Veterans Institute for Research
Last refreshed: 10 March 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03652948.

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