NCT03651453 is a NA clinical trial of Decision aid in HIV Infections, sponsored by Yale University.

Who is sponsoring NCT03651453?

NCT03651453 is sponsored by Yale University.

What drugs are being tested in NCT03651453?

Interventions in NCT03651453: Decision aid, Standard care.

What condition does NCT03651453 study?

NCT03651453 studies HIV Infections, Substance Abuse.

Is NCT03651453 still recruiting?

NCT03651453 is currently completed. Last updated 28 July 2021.

Last reviewed 2021-07-28 · How we verify

NCT03651453

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatment Settings

Completed NA Last updated 28 July 2021

What this trial tests

NA trial testing Decision aid in HIV Infections in 164 participants. Completed in 11 June 2020.

Timeline

15 October 2018

Primary endpoint
11 June 2020

11 June 2020

Quick facts

Lead sponsor	Yale University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	164
Start date	15 October 2018
Primary completion	11 June 2020
Estimated completion	11 June 2020
Sites	1 location across United States

Drugs / interventions tested

Decision aid
Standard care — full drug profile →

Conditions studied

HIV Infections — all drugs for HIV Infections →
Substance Abuse — all drugs for Substance Abuse →

Sponsor

Yale University

Who can join

18 and older, female only, with HIV Infections or Substance Abuse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To develop and test the effect of a patient-centered HIV prevention decision aid on HIV pre-exposure prophylaxis (PrEP) uptake among women with substance use disorders (SUD) in treatment.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

"A good mother": Impact of motherhood identity on women's substance use and engagement in treatment across the lifespan.
Adams ZM, Ginapp CM, Price CR, Qin Y, et al · · 2021 · cited 41× · PMID 34118710 · DOI 10.1016/j.jsat.2021.108474
Women's Decision-Making about PrEP for HIV Prevention in Drug Treatment Contexts.
Qin Y, Price C, Rutledge R, Puglisi L, et al · · 2020 · cited 25× · PMID 31918605 · DOI 10.1177/2325958219900091
Preference for and Efficacy of a PrEP Decision Aid for Women with Substance Use Disorders.
Meyer J, Price C, Tracey D, Sharpless L, et al · · 2021 · cited 22× · PMID 34511887 · DOI 10.2147/ppa.s315543
Overlapping needs for sexual and reproductive health and HIV prevention in women with substance use disorders.
Gibson B, Hoff E, Haas A, Adams ZM, et al · · 2022 · cited 8× · PMID 35023410 · DOI 10.1177/17455065211070543

Verify or expand the search:

Other trials of Decision aid

Trials testing the same drug.

NCT06920927 — Feasibility and Pilot Testing of "My Heart and CKD" Online Shared Decision Aid · NA · not yet recruiting
NCT06247371 — Impact of a Novel Heart Failure Medication Decision Aid · NA · completed
NCT06382194 — Decision Making Tool for Firearm Storage · NA · completed
NCT06189807 — Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD) · NA · active not recruiting
NCT05182008 — A Patient Decision Aid for Method of Early Abortion: a Randomized Control Trial · NA · completed

Other recruiting trials for HIV Infections

Currently open trials in the same condition.

NCT07225530 — Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR) · NA · recruiting
NCT07202546 — A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · recruiting
NCT06694753 — Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall · Phase 1 · recruiting
NCT07235852 — Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention · NA · recruiting
NCT06665646 — Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Ad · Phase 1 · recruiting

Other Yale University trials

Trials by the same sponsor.

NCT06900998 — Pilot Study: Effects of Nimodipine on Alcohol Drinking · Phase 2 · not yet recruiting
NCT04910984 — Developing a Chatbot to Promote HIV Testing · NA · not yet recruiting
NCT07458087 — Accuracy of the Accuro 3S · NA · not yet recruiting
NCT07398404 — A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Pa · Phase 1, PHASE2 · not yet recruiting
NCT07305324 — Improving Liver Fibrosis Diagnosis in Primary Care Using FibroX AI · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03651453 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yale University
Last refreshed: 28 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03651453.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing