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NCT03649022

"Ventricular Tachycardia Ablation Registry".

Status unknown Last updated 14 April 2020
What this trial tests

trial testing Catheter ablation in Ventricular Tachycardia in 312 participants. Status unknown.

Timeline
25 July 2017
Primary endpoint
31 January 2021
31 January 2021

Quick facts

Lead sponsorPaolo Della Bella
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment312
Start date25 July 2017
Primary completion31 January 2021
Estimated completion31 January 2021
Sites1 location across Italy

Drugs / interventions tested

Conditions studied

Sponsor

Paolo Della Bella

Who can join

18 and older, any sex, with Ventricular Tachycardia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Catheter ablation of Ventricular Tachycardias is a well-established approach in clinical practice in patients with Implantable Cardioverter Defibrillator (ICD) implanted. Previous studies have shown a significant reduction in appropriate shocks (\~ 20%) and a significant reduction in hospitalizations for cardiovascular reasons (\~ 12%) in patients with ischemic heart disease treated with ablation. Recent works have also shown the effectiveness of the ablation procedure using as procedural target the reduction of late potentials. However, actually it is necessary to have an homogenize and accepted mapping scheme in Sinus Rhythm to ablate Ventricular Tachycardias related to scar substrate in patients with: * Previous MI * Previous myocarditis * Arrhythmogenic Right Ventricular Dysplasia (ARVD) * Idiopathic Dilated Cardiomyopathy (IDCM) Scope of the registry is to collect data during cardiac mapping in Sinus Rhythm in patients indicated for Ventricular Tachycardia ablation, that will be performed per clinical practice, by using the St. Jude Medical EnSiteTM PrecisionTM mapping system. The objective of the present registry is: to assess the acute and long-term efficacy of the strategy of substrate abolition (abolishment of complex and late potentials) guided by electroanatomic mapping with Precision software.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Matching Ablation Endpoints to Long-Term Outcome: The Prospective Multicenter Italian Ventricular Tachycardia Ablation Registry.
    Radinovic A, Peretto G, Sgarito G, Cauti FM, et al · · 2023 · cited 9× · PMID 36752462 · DOI 10.1016/j.jacep.2022.10.038

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Other trials of Catheter ablation

Trials testing the same drug.

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Currently open trials in the same condition.

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03649022.

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