Who is sponsoring NCT03646825?

NCT03646825 is sponsored by Colorado Center for Reproductive Medicine.

What drugs are being tested in NCT03646825?

Interventions in NCT03646825: Natural Antioxidant supplement.

What condition does NCT03646825 study?

NCT03646825 studies Observe Effect of Antioxidant on Sperm DNA Fragmention.

Is NCT03646825 still recruiting?

NCT03646825 is currently terminated. Last updated 23 February 2023.

Last reviewed 2023-02-23 · How we verify

NCT03646825

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Natural Antioxidant Supplement on Sperm DNA Fragmentation

Terminated Last updated 23 February 2023

What this trial tests

trial testing Natural Antioxidant supplement in Observe Effect of Antioxidant on Sperm DNA Fragmention in 54 participants. Terminated before completion.

Timeline

1 August 2018

Primary endpoint
15 June 2022

1 October 2022

Quick facts

Lead sponsor	Colorado Center for Reproductive Medicine
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	54
Start date	1 August 2018
Primary completion	15 June 2022
Estimated completion	1 October 2022
Sites	1 location across United States

Drugs / interventions tested

Natural Antioxidant supplement

Conditions studied

Observe Effect of Antioxidant on Sperm DNA Fragmention — all drugs for Observe Effect of Antioxidant on Sperm DNA Fragmention →

Sponsor

Colorado Center for Reproductive Medicine — full company profile →

Who can join

Adults 18 to 55, male only, with Observe Effect of Antioxidant on Sperm DNA Fragmention. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Observational study to see the effect of use of natural Antioxidant supplement on sperm DNA fragmentation. Subjects will take the natural antioxidant for 3 months prior to repeat testing.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Mitigating the Effects of Oxidative Sperm DNA Damage.
Pini T, Makloski R, Maruniak K, Schoolcraft WB, et al · · 2020 · cited 6× · PMID 32640607 · DOI 10.3390/antiox9070589

Verify or expand the search:

Other Colorado Center for Reproductive Medicine trials

Trials by the same sponsor.

NCT06633120 — In Vitro Maturation of Human Eggs · NA · recruiting
NCT04472156 — A Prospective Study of a Mosaic Embryo Transfer · NA · recruiting
NCT04445025 — Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis · EARLY_PHASE1 · completed
NCT03717441 — DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03646825 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Colorado Center for Reproductive Medicine
Last refreshed: 23 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03646825.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing