NCT03645343 is a NA clinical trial of Activator in Malocclusion, Angle Class II, sponsored by Damascus University.

Who is sponsoring NCT03645343?

NCT03645343 is sponsored by Damascus University.

What drugs are being tested in NCT03645343?

Interventions in NCT03645343: Activator, Twin Block.

What condition does NCT03645343 study?

NCT03645343 studies Malocclusion, Angle Class II, Retrognathism, TMJ.

Is NCT03645343 still recruiting?

NCT03645343 is currently completed. Last updated 5 February 2020.

Last reviewed 2020-02-05 · How we verify

NCT03645343

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Functional Treatment of Patients With Backward Positioned Chins on the Jaw Joint and Movements

Completed NA Last updated 5 February 2020

What this trial tests

NA trial testing Activator in Malocclusion, Angle Class II in 66 participants. Completed in 19 November 2019.

Timeline

15 June 2018

Primary endpoint
19 March 2019

19 November 2019

Quick facts

Lead sponsor	Damascus University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	66
Start date	15 June 2018
Primary completion	19 March 2019
Estimated completion	19 November 2019
Sites	1 location across Syria

Drugs / interventions tested

Activator
Twin Block — full drug profile →

Conditions studied

Malocclusion, Angle Class II — all drugs for Malocclusion, Angle Class II →
Retrognathism — all drugs for Retrognathism →
TMJ — all drugs for TMJ →

Sponsor

Damascus University

Who can join

Adults 10 to 13, any sex, with Malocclusion, Angle Class II or Retrognathism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients with class II malocclusion and retrognathic mandibles will be treated using functional appliances and asses the remodeling that is expected to occur in the temporomandibular joint (TMJ) using cone-beam computed tomography (CBCT) images and we will register mandibular movements using electronic axiograph ( a specific apparatus used to record jaw movements in three dimensions). There are three groups : 1. Activator Group 2. Twin block Group 3. Control Group with no treatment. Patients will be allocated to the three groups randomly. Data will be collected using three different approaches: * CBCT images before treatment and 12 months after treatment * Axiograph registrations before treatment and 12 months after treatment

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Malocclusion, Angle Class II

Currently open trials in the same condition.

NCT05950581 — Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates · NA · recruiting
NCT06743360 — Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implants · active not recruiting
NCT06297109 — Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery · NA · active not recruiting

Other Damascus University trials

Trials by the same sponsor.

NCT07532161 — Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery · NA · not yet recruiting
NCT07515612 — The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic. · NA · recruiting
NCT07272798 — Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension · recruiting
NCT07426523 — Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. · NA · completed
NCT07366788 — Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03645343 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Damascus University
Last refreshed: 5 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03645343.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing