NCT03640741 is a clinical trial of Laparoscopy in Increase in Intra-abdominal Pressure, sponsored by Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences.

What drugs are being tested in NCT03640741?

Interventions in NCT03640741: Laparoscopy.

What condition does NCT03640741 study?

NCT03640741 studies Increase in Intra-abdominal Pressure, Increase in Intracranial Pressure (ICP), Laparoscopy, Cerebral Perfusion and Oxygenation.

Is NCT03640741 still recruiting?

NCT03640741 is currently completed. Last updated 21 August 2018.

Last reviewed 2018-08-21 · How we verify

NCT03640741

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Changes in Cerebral Oxygenation Studies During Laparoscopy Procedure

Completed Last updated 21 August 2018

What this trial tests

trial testing Laparoscopy in Increase in Intra-abdominal Pressure in 17 participants. Completed in 18 December 2017.

Timeline

11 July 2016

Primary endpoint
25 July 2016

18 December 2017

Quick facts

Lead sponsor	Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences
Status	Completed
Study type	OBSERVATIONAL
Enrollment	17
Start date	11 July 2016
Primary completion	25 July 2016
Estimated completion	18 December 2017

Drugs / interventions tested

Laparoscopy — full drug profile →

Conditions studied

Increase in Intra-abdominal Pressure — all drugs for Increase in Intra-abdominal Pressure →
Increase in Intracranial Pressure (ICP) — all drugs for Increase in Intracranial Pressure (ICP) →
Laparoscopy — all drugs for Laparoscopy →
Cerebral Perfusion and Oxygenation — all drugs for Cerebral Perfusion and Oxygenation →

Sponsor

Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences

Who can join

18 and older, female only, with Increase in Intra-abdominal Pressure or Increase in Intracranial Pressure (ICP). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure. The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Influence of intra-abdominal pressure on the amplitude of fluctuations of cerebral hemoglobin concentration in the respiratory band.
Sawosz P, Kacprzak M, Pulawski P, Morawiec M, et al · · 2019 · cited 4× · PMID 31467788 · DOI 10.1364/boe.10.003434

Verify or expand the search:

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Trials testing the same drug.

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Other Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences trials

Trials by the same sponsor.

NCT02902588 — Blood-brain Barrier Permeability Study in Adults With Meningitis · NA · terminated

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03640741 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences
Last refreshed: 21 August 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03640741.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing