Who is sponsoring NCT03639831?

NCT03639831 is sponsored by Activ'inside.

What drugs are being tested in NCT03639831?

Interventions in NCT03639831: Proprietary, standardized botanical extract, Placebo (maltodextrin).

What condition does NCT03639831 study?

NCT03639831 studies Mood Disorders.

Is NCT03639831 still recruiting?

NCT03639831 is currently completed. Last updated 10 April 2019.

Last reviewed 2019-04-10 · How we verify

NCT03639831

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

ACUTE AND CHRONIC EFFECTS OF A BOTANICAL EXTRACT ON ANXIETY, PERCEIVED STRESS, MOOD AND CORTISOL IN HEALTHY ADULTS

Completed NA Last updated 10 April 2019

What this trial tests

NA trial testing Proprietary, standardized botanical extract in Mood Disorders in 65 participants. Completed in 31 March 2019.

Timeline

6 November 2017

Primary endpoint
15 November 2018

31 March 2019

Quick facts

Lead sponsor	Activ'inside
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	65
Start date	6 November 2017
Primary completion	15 November 2018
Estimated completion	31 March 2019
Sites	1 location across United Kingdom

Drugs / interventions tested

Proprietary, standardized botanical extract
Placebo (maltodextrin)

Conditions studied

Mood Disorders — all drugs for Mood Disorders →

Sponsor

Activ'inside

Who can join

Adults 18 to 60, any sex, with Mood Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Mood disorders, including depression and anxiety, are one of the main causes of the overall disease burden worldwide. In recent years, the efficacy of certain botanicals as an alternative solution for depression has been evaluated in a number of clinical trials. However, only few studies looked at the effects of these botanicals on mood in healthy subjects. The aim of the proposed randomised, double-blind, placebo-controlled, parallel groups methodology is to assess the acute and chronic effects of daily supplementation with a proprietary and standardized botanical extract in comparison to placebo in healthy adults aged 18-60 years with self-reported low mood.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Depression and Its Phytopharmacotherapy-A Narrative Review.
Dobrek L, Głowacka K. · · 2023 · cited 72× · PMID 36902200 · DOI 10.3390/ijms24054772
Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial.
Jackson PA, Forster J, Khan J, Pouchieu C, et al · · 2020 · cited 37× · PMID 33598475 · DOI 10.3389/fnut.2020.606124

Verify or expand the search:

Other recruiting trials for Mood Disorders

Currently open trials in the same condition.

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NCT06412315 — 7T Amygdala and Citalopram Study · NA · recruiting

Other Activ'inside trials

Trials by the same sponsor.

NCT07013539 — Efficacy of a Food Supplement in Relieving Premenstrual Syndrome Symptoms · NA · active not recruiting
NCT06545552 — Efficacy and Safety of a Dietary Supplement on Hair Growth and Hair Health in Female With Acute Telogen Effluvium · NA · completed
NCT05098093 — Bioavailabity of the Major Metabolites of a Botanical Extract, in Healthy Adults · NA · completed
NCT04697589 — Acute Effect of a Proprietary Botanical Blend Rich in Polyphenols on Flow-mediated Dilation in Healthy Subjects · NA · completed
NCT04523870 — Acute Effects of a Botanical Extract and Its Main Volatile Compound on Stress Response in Healthy Adults · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03639831 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Activ'inside
Last refreshed: 10 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03639831.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing