Who is sponsoring NCT03637998?

NCT03637998 is sponsored by University of Connecticut.

What drugs are being tested in NCT03637998?

Interventions in NCT03637998: Problem-solving Pain to Enhance Living Well (PROPEL).

What condition does NCT03637998 study?

NCT03637998 studies Chronic Low Back Pain, Self-Management.

Is NCT03637998 still recruiting?

NCT03637998 is currently completed. Last updated 28 November 2023.

Last reviewed 2023-11-28 · How we verify

NCT03637998: PROPEL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain

Completed NA Last updated 28 November 2023

What this trial tests

NA trial testing Problem-solving Pain to Enhance Living Well (PROPEL) in Chronic Low Back Pain in 40 participants. Completed in 31 December 2021.

Timeline

21 September 2018

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	University of Connecticut
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	40
Start date	21 September 2018
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	1 location across United States

Drugs / interventions tested

Problem-solving Pain to Enhance Living Well (PROPEL)

Conditions studied

Chronic Low Back Pain — all drugs for Chronic Low Back Pain →
Self-Management — all drugs for Self-Management →

Sponsor

University of Connecticut

Who can join

Adults 18 to 60, any sex, with Chronic Low Back Pain or Self-Management. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress and kinesiphobia. The purpose is to understand the initial efficacy of self-management (SM) strategies on each of these contextual variables, in an effort to inform a personalized approach to managing chronic low back pain and its effect on improved health outcomes.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effects of Physical Activity on Neurophysiological and Gene Expression Profiles in Chronic Back Pain: Study Protocol.
Kim K, Ramesh D, Perry M, Bernier KM, et al · · 2020 · cited 8× · PMID 31834118 · DOI 10.1097/nnr.0000000000000400
Pain self-management plus activity tracking and nurse-led support in adults with chronic low back pain: feasibility and acceptability of the problem-solving pain to enhance living well (PROPEL) intervention.
Xu W, Zhang Y, Wang Z, Dorsey SG, et al · · 2023 · cited 6× · PMID 37355622 · DOI 10.1186/s12912-023-01365-y

Verify or expand the search:

Other recruiting trials for Chronic Low Back Pain

Currently open trials in the same condition.

NCT07463729 — Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome · NA · recruiting
NCT07415941 — MBM and taVNS for Low Back Pain and Depressive Symptoms · NA · recruiting
NCT06419439 — Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression · Phase 2 · recruiting
NCT07241559 — Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection in Chronic Low Back Pain · NA · recruiting
NCT07132762 — The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Bac · NA · recruiting

Other University of Connecticut trials

Trials by the same sponsor.

NCT06794840 — JomCare Study - A Harm Reduction Study · NA · not yet recruiting
NCT07238556 — A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors · NA · recruiting
NCT06381921 — Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain · NA · recruiting
NCT06393725 — Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions · NA · recruiting
NCT04989309 — Left and Right Hemisphere Contributions to Speech Perception · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03637998 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Connecticut
Last refreshed: 28 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03637998.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing