Who is sponsoring NCT03635645?

NCT03635645 is sponsored by University of Michigan.

What condition does NCT03635645 study?

NCT03635645 studies Retinitis Pigmentosa.

Is NCT03635645 still recruiting?

NCT03635645 is currently recruiting now. Last updated 14 December 2022.

Last reviewed 2022-12-14 · How we verify

NCT03635645

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Experimental and Clinical Studies of Retinal Stimulation

Recruiting now NA Last updated 14 December 2022

What this trial tests

NA trial testing New visual processing unit (VPU) with asymmetric waveforms in Retinitis Pigmentosa in 20 participants. Currently enrolling.

Timeline

30 October 2017

Primary endpoint
30 October 2023

30 October 2023

Quick facts

Lead sponsor	University of Michigan
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	20
Start date	30 October 2017
Primary completion	30 October 2023
Estimated completion	30 October 2023
Sites	1 location across United States

Drugs / interventions tested

New visual processing unit (VPU) with asymmetric waveforms
New VPU with bipolar stimulation

Conditions studied

Retinitis Pigmentosa — all drugs for Retinitis Pigmentosa →

Sponsor

University of Michigan

Who can join

Adults 25 to 89, any sex, with Retinitis Pigmentosa. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will evaluate new methods of retinal stimulation and training with the goal of improving the visual ability of retinal prosthesis participants.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Contemporary approaches to visual prostheses.
Mirochnik RM, Pezaris JS. · · 2019 · cited 32× · PMID 31167653 · DOI 10.1186/s40779-019-0206-9
A Patient-Specific Computational Framework for the Argus II Implant.
Finn KE, Zander HJ, Graham RD, Lempka SF, et al · · 2020 · cited 17× · PMID 33748766 · DOI 10.1109/ojemb.2020.3001563
The effect of waveform asymmetry on perception with epiretinal prostheses.
Haji Ghaffari D, Finn KE, Jeganathan VSE, Patel U, et al · · 2020 · cited 14× · PMID 32590371 · DOI 10.1088/1741-2552/aba07e
Patient-specific computational models of retinal prostheses.
Kish KE, Yuan A, Weiland JD. · · 2023 · cited 5× · PMID 38097732 · DOI 10.1038/s41598-023-49580-6
Clinical Progress and Optimization of Information Processing in Artificial Visual Prostheses.
Wang J, Wang J, Zhao R, Li P, et al · · 2022 · cited 4× · PMID 36081002 · DOI 10.3390/s22176544

Verify or expand the search:

Other recruiting trials for Retinitis Pigmentosa

Currently open trials in the same condition.

NCT06891885 — A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years · Phase 1, PHASE2 · recruiting
NCT07408232 — A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP) · Phase 1, PHASE2 · recruiting
NCT07228793 — Natural History Study of Patients With EYS-Associated RP · recruiting
NCT06319872 — The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration · Phase 1 · recruiting
NCT06936787 — An Open-label, Dose-ascending Study of IGT001 for Retinitis Pigmentosa · Phase 1 · recruiting

Other University of Michigan trials

Trials by the same sponsor.

NCT07536919 — Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation · NA · not yet recruiting
NCT05509842 — Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD) · NA · not yet recruiting
NCT06311188 — Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness · NA · not yet recruiting
NCT07471646 — Effects of Ramadan Fasting With Exercise on Cardiometabolic Health · NA · not yet recruiting
NCT06671925 — A Community Health Worker-Led Program for Chronic Pain and Loneliness in Older Adults · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03635645 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Michigan
Last refreshed: 14 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03635645.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing