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NCT03634176
Optic Nerve Sheath Diameter in Retrobulbar Ultrasound as a Surrogate Measure for Intracranial Pressure Before and After Non-invasive Strategies
trial testing optical nerve sheet diameter in Intracranial Hypertension in 90 participants. Completed in 30 September 2018.
30 August 2018
Quick facts
| Lead sponsor | Hospital Dr. Miguel Pérez Carreño |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 90 |
| Start date | 1 February 2017 |
| Primary completion | 30 August 2018 |
| Estimated completion | 30 September 2018 |
| Sites | 1 location across Venezuela |
Drugs / interventions tested
- optical nerve sheet diameter
Conditions studied
- Intracranial Hypertension — all drugs for Intracranial Hypertension →
- Optic Nerve Sheath Diameter — all drugs for Optic Nerve Sheath Diameter →
Sponsor
Hospital Dr. Miguel Pérez Carreño
Who can join
Adults 18 to 65, any sex, with Intracranial Hypertension or Optic Nerve Sheath Diameter. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Measurement of the diameter of the sheath of the optic nerve in patients hospitalized in intensive care, with increased intracranial pressure (\> 20mmHg) as a substitute measure for diagnosis and follow-up before and after different non-invasive strategies. Three groups were created in which, through strategies already proven and non-invasive (mannitol, hypertonic solution 7.5% NaCl, reverse trendelenburg) to decrease the intracranial pressure, the optic nerve diameter measurement was performed and simultaneously the investigators monitored intracranial pressure through an intraventricular catheter continuously to determine if both correspond
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Optic Nerve Sheath Diameter in retrobulbar ultrasound as a surrogate measure for intracranial pressure before and after non-invasive strategies.
diab as, Martínez B, Gámez A, Bucott Y. · · 2019 · DOI 10.21203/rs.2.16537/v1
Verify or expand the search:
- PubMed search for NCT03634176
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03634176 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Dr. Miguel Pérez Carreño
- Last refreshed: 8 November 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03634176.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing