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NCT03625414
Tissue Alterations in Aggressive and Chronic Periodontitis
trial in Localized Aggressive Periodontitis in 45 participants. Completed in 1 June 2018.
1 February 2018
Quick facts
| Lead sponsor | Tokat Gaziosmanpasa University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 45 |
| Start date | 1 February 2017 |
| Primary completion | 1 February 2018 |
| Estimated completion | 1 June 2018 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Localized Aggressive Periodontitis — all drugs for Localized Aggressive Periodontitis →
- Chronic Periodontitis — all drugs for Chronic Periodontitis →
Sponsor
Tokat Gaziosmanpasa University
Who can join
Adults 30 to 45, any sex, with Localized Aggressive Periodontitis or Chronic Periodontitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Present study intended to compare diseased and healthy sites in chronic and aggressive periodontitis with healthy individuals. The investigators suggest that even unaffected healthy sites of both chronic and aggressive periodontitis patients exhibit subclinical inflammation and tissue destruction with decreased fibroblast cell counts and increased inflammatory cell counts. Investigators also suggest that a possible mechanism which might play a role in the disease progression might occur via a disbalance between matrix metalloproteinases and their inhibitors, and increased hypoxia in diseased sites.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03625414
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03625414 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tokat Gaziosmanpasa University
- Last refreshed: 13 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03625414.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing