18 and older, female only, with Depression or Pregnancy Related. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Number of Participants Experiencing Relapse of DepressionPrimary· Randomization through 6 months postpartum
Depression relapse from randomization through 6 month postpartum
Group
Value
95% CI
Digital Delivery of MBCT (Mindful Mood Balance for Moms)
81
Usual Care
111
Adverse events — posted to ClinicalTrials.gov
Time frame: March 12, 2019 to September 12, 2021 (18 months).
Reporting threshold: 0%.
Adverse-event reports describe events observed during the trial — not all are caused by the drug.
Digital Delivery of MBCT (Mindful Mood Balance for Moms)
Serious: 0/249 (0%)
Deaths: 0/249
Usual Care
Serious: 0/251 (0%)
Deaths: 0/251
Other adverse events (1 terms — click to expand)
Reaction
System
Digital Delivery of MBCT (…
Usual Care
All events categorized as "unexpected" and "non-Severe"
The purpose of this investigation is to conduct a pragmatic effectiveness trial comparing digital mindfulness-based cognitive therapy (MBCT) plus usual care to usual care (UC) only among euthymic pregnant women with recurrent depression treated with antidepressants.
In the supplemental arms we will investigate the prevalence, severity, longitudinal course, correlates, and predictors of suicidal ideation and behavior among women during pregnancy and the postpartum period.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
Last refreshed: 6 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03623620.