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NCT03621579
Analysis of Retinal Nerve Fiber Layer and Macular Thickness After Congenital Cataract Surgery
NA trial testing cataract surgery in Congenital Cataract in 60 participants. Completed in 1 April 2018.
1 March 2018
Quick facts
| Lead sponsor | Wenzhou Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 March 2017 |
| Primary completion | 1 March 2018 |
| Estimated completion | 1 April 2018 |
| Sites | 2 locations across China |
Drugs / interventions tested
- cataract surgery — full drug profile →
Conditions studied
- Congenital Cataract — all drugs for Congenital Cataract →
Sponsor
Wenzhou Medical University
Who can join
Adults 1 Month to 12, any sex, with Congenital Cataract. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the retinal nerve fiber layer. However, there are different opinions about the effect of amblyopia on the optic nerve fiber thickness around the optic disc at home and abroad. Investigators have performed "cataract extraction with IOL implantation" on children with bilateral and unilateral congenital cataract. Investigators used OCT biometry to measure children's the retinal nerve fiber layer (RNFLT) and macular thickness (CMT) before and after surgery. Investigators dynamically observed changes in RNFL and CMT to explore the retinal mechanism of form deprivation amblyopia and help guide the clinical correct understanding of postoperative follow-up time.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03621579
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of cataract surgery
Trials testing the same drug.
- NCT06658119 — Clinical Evaluation of Extended Depth-of-focus Intraocular Lens in Refractive Cataract Surgery: a Randomized Controlled · NA · recruiting
- NCT06505096 — A Comparative Study of the Results of Dynamic and OPD Static Measurement of Pupil Diameter Before and After Cataract Sur · not yet recruiting
- NCT05718076 — Trifocal Intraocular Lens in High Myopic Patients With Different Meta-PM Grading · unknown
- NCT06708806 — Cell Ongrowth and Biocompatibility Study of Two Different (Hydrophobic Acrylic) Intraocular Lenses: IOL XY1 vs. IOL XY1A · NA · completed
- NCT04931277 — Stepped Surgery in Uveitic Cataract: A Novel Approach to a Quiet Eye · NA · completed
Other recruiting trials for Congenital Cataract
Currently open trials in the same condition.
- NCT05136209 — Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy · NA · recruiting
- NCT07070037 — Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery · recruiting
- NCT03063216 — Shanghai Pediatric Cataract Study · recruiting
Other Wenzhou Medical University trials
Trials by the same sponsor.
- NCT06905938 — Comparing Monofocal IOLs in Highly Myopic Cataract Patients · not yet recruiting
- NCT06892470 — Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses · active not recruiting
- NCT06751342 — Using Psychophysics Methods to Investigate Sensory Dominance After Cataract Surgery · active not recruiting
- NCT06707740 — Comparison of the Effect of Capsular Bend on the Rotational Stability Between Two Toric Intraocular Lenses · active not recruiting
- NCT06091722 — Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03621579 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wenzhou Medical University
- Last refreshed: 8 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03621579.
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